MGP Database

New search | Record Overview | Ontology/Pathway Information | Domain Information | UniProt Annotations | Related Proteins
MGP002779

UniProt Annotations

Entry Information
Gene Namechemokine (C-C motif) ligand 7
Protein EntryCCL7_HUMAN
UniProt IDP80098
SpeciesHuman
Comments
Comment typeDescription
FunctionChemotactic factor that attracts monocytes and eosinophils, but not neutrophils. Augments monocyte anti-tumor activity. Also induces the release of gelatinase B. This protein can bind heparin. Binds to CCR1, CCR2 and CCR3.
PtmO-glycosylated.
Sequence CautionSequence=CAA50405.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=CAA50406.1; Type=Erroneous initiation; Evidence={ECO:0000305}; Sequence=CAA51055.1; Type=Erroneous initiation; Evidence={ECO:0000305};
SimilarityBelongs to the intercrine beta (chemokine CC) family. {ECO:0000305}.
Subcellular LocationSecreted.
SubunitMonomer. {ECO:0000269|PubMed:8898111}.
Web ResourceName=Wikipedia; Note=CCL7 entry; URL="http://en.wikipedia.org/wiki/CCL7";
  logo