MGP Database

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MGP002798

Ontology/Pathway Information

Entrez Gene ID6390
Gene Namesuccinate dehydrogenase complex, subunit B, iron sulfur (Ip)
Gene Symbol SDHB
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0005743 ISS:UniProtKBCmitochondrial inner membrane
GO:0005749 ISS:UniProtKBCmitochondrial respiratory chain complex II
GO:0005739 IDA:HPACmitochondrion
GO:0051537 ISS:UniProtKBF2 iron, 2 sulfur cluster binding
GO:0051538 ISS:UniProtKBF3 iron, 4 sulfur cluster binding
GO:0051539 ISS:UniProtKBF4 iron, 4 sulfur cluster binding
GO:0009055 IEA:InterProFelectron carrier activity
GO:0046872 IEA:UniProtKB-KWFmetal ion binding
GO:0008177 IEA:UniProtKB-ECFsuccinate dehydrogenase (ubiquinone) activity
GO:0048039 ISS:UniProtKBFubiquinone binding
GO:0009060 TAS:ProtIncPaerobic respiration
GO:0044237 TAS:ReactomePcellular metabolic process
GO:0022904 TAS:ReactomePrespiratory electron transport chain
GO:0044281 TAS:ReactomePsmall molecule metabolic process
GO:0006105 IEA:EnsemblPsuccinate metabolic process
GO:0006099 TAS:ReactomePtricarboxylic acid cycle
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_1785Citric acid cycle (TCA cycle)
REACT_111217Metabolism
REACT_1046Pyruvate metabolism and Citric Acid (TCA) cycle
REACT_22393Respiratory electron transport
REACT_6305Respiratory electron transport, ATP synthesis by chemiosmotic coupling, and heat production by uncoupling proteins.
REACT_111083The citric acid (TCA) cycle and respiratory electron transport
SMP Pathway Links
SMP IDDescription
SMP005492-ketoglutarate dehydrogenase complex deficiency
SMP00057Citric Acid Cycle
SMP00546Congenital lactic acidosis
SMP00547Fumarase deficiency
SMP00548Mitochondrial complex II deficiency
SMP00355Mitochondrial Electron Transport Chain
SMP00551Pyruvate dehydrogenase deficiency (E2)
SMP00550Pyruvate dehydrogenase deficiency (E3)
SMP00654Warburg Effect
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