MGP Database

MGP003251

Record overview

MGPD IDMGP003251
Gene ID7334
SpeciesHomo sapiens (Human)
Gene Nameubiquitin-conjugating enzyme E2N
Gene Symbol UBE2N
SynonymsUBC13; UbcH13; HEL-S-71; UbcH-ben; UBCHBEN; UBC13;
Alternate namesubiquitin-conjugating enzyme E2 N; bendless-like ubiquitin conjugating enzyme; bendless-like ubiquitin-conjugating enzyme; epididymis secretory protein Li 71; ubiquitin carrier protein N; ubiquitin-conjugating enzyme E2N (UBC13 homolog, yeast); ubiquitin-conjugating enzyme E2N (homologous to yeast UBC13); ubiquitin-protein ligase N; yeast UBC13 homolog;
Chromosome12
Map Location12q22
EC Number6.3.2.19
SummaryThe modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. Studies in mouse suggest that this protein plays a role in DNA postreplication repair. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for UBE2N

Proteins

ubiquitin-conjugating enzyme E2 N
Refseq ID:NP_003339
Protein GI:4507793
UniProt ID:P61088
mRNA ID:NM_003348
Length:152
RefSeq Status:
MAGLPRRIIKETQRLLAEPVPGIKAEPDESNARYFHVVIAGPQDSPFEGGTFKLELFLPEEYPMAAPKVRFMTKIYHPNVDKLGRICLDILKDKWSPALQ
IRTVLLSIQALLSAPNPDDPLANDVAEQWKTNEAQAIETARAWTRLYAMNNI
 
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