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MGP003281

Record overview

MGPD IDMGP003281
Gene ID7398
SpeciesHomo sapiens (Human)
Gene Nameubiquitin specific peptidase 1
Gene Symbol USP1
SynonymsUBP;
Alternate namesubiquitin carboxyl-terminal hydrolase 1; deubiquitinating enzyme 1; hUBP; ubiquitin carboxyl terminal hydrolase 1; ubiquitin specific processing protease 1; ubiquitin specific protease 1; ubiquitin thioesterase 1; ubiquitin thiolesterase 1; ubiquitin-specific-processing protease 1;
Chromosome1
Map Location1p31.3
EC Number3.4.19.12
SummaryThis gene encodes a member of the ubiquitin-specific processing (UBP) family of proteases that is a deubiquitinating enzyme (DUB) with His and Cys domains. This protein is located in the cytoplasm and cleaves the ubiquitin moiety from ubiquitin-fused precursors and ubiquitinylated proteins. The protein specifically deubiquitinates a protein in the Fanconi anemia (FA) DNA repair pathway. Alternate transcriptional splice variants have been characterized. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for USP1

Proteins

ubiquitin carboxyl-terminal hydrolase 1
Refseq ID:NP_003359
Protein GI:31543910
UniProt ID:O94782
mRNA ID:NM_003368
Length:785
RefSeq Status:
MPGVIPSESNGLSRGSPSKKNRLSLKFFQKKETKRALDFTDSQENEEKASEYRASEIDQVVPAAQSSPINCEKRENLLPFVGLNNLGNTCYLNSILQVLY
FCPGFKSGVKHLFNIISRKKEALKDEANQKDKGNCKEDSLASYELICSLQSLIISVEQLQASFLLNPEKYTDELATQPRRLLNTLRELNPMYEGYLQHDA
QEVLQCILGNIQETCQLLKKEEVKNVAELPTKVEEIPHPKEEMNGINSIEMDSMRHSEDFKEKLPKGNGKRKSDTEFGNMKKKVKLSKEHQSLEENQRQT
RSKRKATSDTLESPPKIIPKYISENESPRPSQKKSRVKINWLKSATKQPSILSKFCSLGKITTNQGVKGQSKENECDPEEDLGKCESDNTTNGCGLESPG
NTVTPVNVNEVKPINKGEEQIGFELVEKLFQGQLVLRTRCLECESLTERREDFQDISVPVQEDELSKVEESSEISPEPKTEMKTLRWAISQFASVERIVG
EDKYFCENCHHYTEAERSLLFDKMPEVITIHLKCFAASGLEFDCYGGGLSKINTPLLTPLKLSLEEWSTKPTNDSYGLFAVVMHSGITISSGHYTASVKV
TDLNSLELDKGNFVVDQMCEIGKPEPLNEEEARGVVENYNDEEVSIRVGGNTQPSKVLNKKNVEAIGLLGGQKSKADYELYNKASNPDKVASTAFAENRN
SETSDTTGTHESDRNKESSDQTGINISGFENKISYVVQSLKEYEGKWLLFDDSEVKVTEEKDFLNSLSPSTSPTSTPYLLFYKKL
 
ubiquitin carboxyl-terminal hydrolase 1
Refseq ID:NP_001017415
Protein GI:63053522
UniProt ID:O94782
mRNA ID:NM_001017415
Length:785
RefSeq Status:
Protein sequence is identical to GI:31543910 (mRNA isoform)
 
ubiquitin carboxyl-terminal hydrolase 1
Refseq ID:NP_001017416
Protein GI:63053524
UniProt ID:O94782
mRNA ID:NM_001017416
Length:785
RefSeq Status:
Protein sequence is identical to GI:31543910 (mRNA isoform)
 
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