MGP Database

MGP003295

Ontology/Pathway Information

Entrez Gene ID	7424
Gene Name	vascular endothelial growth factor C
Gene Symbol	VEGFC
Species	Homo sapiens

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0005576	TAS:Reactome	C	extracellular region
GO:0005615	IEA:Ensembl	C	extracellular space
GO:0016020	IEA:InterPro	C	membrane
GO:0031093	TAS:Reactome	C	platelet alpha granule lumen
GO:0042056	IDA:UniProtKB	F	chemoattractant activity
GO:0001525	IEA:UniProtKB-KW	P	angiogenesis
GO:0007596	TAS:Reactome	P	blood coagulation
GO:0050930	IDA:UniProtKB	P	induction of positive chemotaxis
GO:0016331	IEA:Ensembl	P	morphogenesis of embryonic epithelium
GO:0045776	IEA:Ensembl	P	negative regulation of blood pressure
GO:0008285	IEA:Ensembl	P	negative regulation of cell proliferation
GO:0009887	IEA:Ensembl	P	organ morphogenesis
GO:0030168	TAS:Reactome	P	platelet activation
GO:0002576	TAS:Reactome	P	platelet degranulation
GO:0050918	IDA:GOC	P	positive chemotaxis
GO:0045766	IEA:Ensembl	P	positive regulation of angiogenesis
GO:0043536	IEA:Ensembl	P	positive regulation of blood vessel endothelial cell migration
GO:0051781	IEA:UniProtKB-KW	P	positive regulation of cell division
GO:0001954	IEA:Ensembl	P	positive regulation of cell-matrix adhesion
GO:0008284	TAS:ProtInc	P	positive regulation of cell proliferation
GO:0050679	IEA:Ensembl	P	positive regulation of epithelial cell proliferation
GO:1901492	IEA:Ensembl	P	positive regulation of lymphangiogenesis
GO:0060754	IDA:UniProtKB	P	positive regulation of mast cell chemotaxis
GO:0002052	IEA:Ensembl	P	positive regulation of neuroblast proliferation
GO:0050731	IEA:Ensembl	P	positive regulation of peptidyl-tyrosine phosphorylation
GO:0031954	IEA:Ensembl	P	positive regulation of protein autophosphorylation
GO:0050714	IEA:Ensembl	P	positive regulation of protein secretion
GO:0030947	IEA:Ensembl	P	regulation of vascular endothelial growth factor receptor signaling pathway
GO:0042493	IEA:Ensembl	P	response to drug
GO:0007165	TAS:ProtInc	P	signal transduction
GO:0006929	TAS:ProtInc	P	substrate-dependent cell migration
GO:0048010	TAS:Reactome	P	vascular endothelial growth factor receptor signaling pathway

REACTOME Pathway Links

REACTOME Pathway ID	Description
REACT_604	Hemostasis
REACT_798	Platelet activation, signaling and aggregation
REACT_318	Platelet degranulation
REACT_1280	Response to elevated platelet cytosolic Ca2+
REACT_12529	Signaling by VEGF
REACT_111102	Signal Transduction
REACT_12583	VEGF binds to VEGFR leading to receptor dimerization
REACT_12380	VEGF ligand-receptor interactions