MGP Database

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MGP004028

Ontology/Pathway Information

Entrez Gene ID9846
Gene NameGRB2-associated binding protein 2
Gene Symbol GAB2
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005737 IDA:UniProtKBCcytoplasm
GO:0005829 TAS:ReactomeCcytosol
GO:0005886 IDA:UniProtKBCplasma membrane
GO:0005547 ISS:UniProtKBFphosphatidylinositol-3,4,5-trisphosphate binding
GO:0043325 ISS:UniProtKBFphosphatidylinositol-3,4-bisphosphate binding
GO:0005068 IDA:UniProtKBFtransmembrane receptor protein tyrosine kinase adaptor activity
GO:0038095 TAS:ReactomePFc-epsilon receptor signaling pathway
GO:0045087 TAS:ReactomePinnate immune response
GO:0030316 IMP:UniProtKBPosteoclast differentiation
GO:0048015 ISS:UniProtKBPphosphatidylinositol-mediated signaling
GO:0008284 IDA:UniProtKBPpositive regulation of cell proliferation
GO:0043306 ISS:UniProtKBPpositive regulation of mast cell degranulation
GO:0007169 IDA:GOCPtransmembrane receptor protein tyrosine kinase signaling pathway
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_75790Cytokine Signaling in Immune system
REACT_116125Disease
REACT_163936Fc epsilon receptor (FCERI) signaling
REACT_19290G beta:gamma signalling through PI3Kgamma
REACT_19184GPCR downstream signaling
REACT_19388G-protein beta:gamma signalling
REACT_1695GPVI-mediated activation cascade
REACT_604Hemostasis
REACT_6900Immune System
REACT_6802Innate Immune System
REACT_27283Interleukin-2 signaling
REACT_23837Interleukin-3, 5 and GM-CSF signaling
REACT_23891Interleukin receptor SHC signaling
REACT_798Platelet activation, signaling and aggregation
REACT_163769Role of LAT2/NTAL/LAB on calcium mobilization
REACT_121141Signaling by FGFR1 fusion mutants
REACT_120999Signaling by FGFR1 mutants
REACT_120736Signaling by FGFR in disease
REACT_121398Signaling by FGFR mutants
REACT_14797Signaling by GPCR
REACT_22232Signaling by Interleukins
REACT_111040Signaling by SCF-KIT
REACT_111102Signal Transduction
SMP Pathway Links
SMP IDDescription
SMP00358Fc Epsilon Receptor I Signaling in Mast Cells
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