MGP Database

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MGP004545

Ontology/Pathway Information

Entrez Gene ID22926
Gene Nameactivating transcription factor 6
Gene Symbol ATF6
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005783 IDA:ParkinsonsUK-UCLCendoplasmic reticulum
GO:0005789 TAS:ReactomeCendoplasmic reticulum membrane
GO:0005794 IDA:ParkinsonsUK-UCLCGolgi apparatus
GO:0000139 TAS:ReactomeCGolgi membrane
GO:0030176 NAS:ParkinsonsUK-UCLCintegral component of endoplasmic reticulum membrane
GO:0016020 IDA:ParkinsonsUK-UCLCmembrane
GO:0005635 TAS:ProtIncCnuclear envelope
GO:0005654 TAS:ReactomeCnucleoplasm
GO:0005634 IDA:ParkinsonsUK-UCLCnucleus
GO:0000977 IDA:UniProtKBFRNA polymerase II regulatory region sequence-specific DNA binding
GO:0003700 IDA:ParkinsonsUK-UCLFsequence-specific DNA binding transcription factor activity
GO:0003713 TAS:ProtIncFtranscription coactivator activity
GO:0006987 TAS:ReactomePactivation of signaling protein activity involved in unfolded protein response
GO:0044267 TAS:ReactomePcellular protein metabolic process
GO:0030968 TAS:BHF-UCLPendoplasmic reticulum unfolded protein response
GO:1990440 IDA:ParkinsonsUK-UCLPpositive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress
GO:0006990 TAS:ProtIncPpositive regulation of transcription from RNA polymerase II promoter involved in unfolded protein response
GO:0006457 TAS:ProtIncPprotein folding
GO:0006357 TAS:ProtIncPregulation of transcription from RNA polymerase II promoter
GO:0006950 TAS:ProtIncPresponse to stress
GO:0007165 TAS:ProtIncPsignal transduction
GO:0006351 IEA:UniProtKB-KWPtranscription, DNA-templated
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_18355ATF4 activates genes
REACT_18423ATF6-alpha activates chaperone genes
REACT_18348ATF6-alpha activates chaperones
REACT_17015Metabolism of proteins
REACT_18277PERK regulates gene expression
REACT_18356Unfolded Protein Response (UPR)
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