MGP Database

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MGP005196

Record overview

MGPD IDMGP005196
Gene ID51497
SpeciesHomo sapiens (Human)
Gene Namenegative elongation factor complex member C/D
Gene Symbol NELFCD
SynonymsTH1; TH1L; NELF-C; NELF-D; HSPC130;
Alternate namesnegative elongation factor C/D; NELF-C/D; TH1 drosophila homolog; TH1-like protein; negative elongation factor proteins C and D; trihydrophobin 1;
Chromosome20
Map Location20q13
SummaryThe NELF complex of proteins interacts with the DSIF protein complex to repress transcriptional elongation by RNA polymerase II. The protein encoded by this gene is an essential part of the NELF complex. Alternative translation initiation site usage results in the formation of two isoforms with different N-termini. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for NELFCD

Proteins

negative elongation factor C/D
Refseq ID:NP_945327
Protein GI:399788586
UniProt ID:Q8IXH7
mRNA ID:NM_198976
Length:599
RefSeq Status:
MRRARSREGMAGAVPGAIMDEDYYGSAAEWGDEADGGQQEDDSGEGEDDAEVQQECLHKFSTRDYIMEPSIFNTLKRYFQAGGSPENVIQLLSENYTAVA
QTVNLLAEWLIQTGVEPVQVQETVENHLKSLLIKHFDPRKADSIFTEEGETPAWLEQMIAHTTWRDLFYKLAEAHPDCLMLNFTVKLISDAGYQGEITSV
STACQQLEVFSRVLRTSLATILDGGEENLEKNLPEFAKMVCHGEHTYLFAQAMMSVLAQEEQGGSAVRRIAQEVQRFAQEKGHDASQITLALGTAASYPR
ACQALGAMLSKGALNPADITVLFKMFTSMDPPPVELIRVPAFLDLFMQSLFKPGARINQDHKHKYIHILAYAASVVETWKKNKRVSINKDELKSTSKAVE
TVHNLCCNENKGASELVAELSTLYQCIRFPVVAMGVLKWVDWTVSEPRYFQLQTDHTPVHLALLDEISTCHQLLHPQVLQLLVKLFETEHSQLDVMEQLE
LKKTLLDRMVHLLSRGYVLPVVSYIRKCLEKLDTDISLIRYFVTEVLDVIAPPYTSDFVQLFLPILENDSIAGTIKTEGEHDPVTEFIAHCKSNFIMVN
 
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