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MGP006076

Record overview

MGPD IDMGP006076
Gene ID83549
SpeciesHomo sapiens (Human)
Gene Nameuridine-cytidine kinase 1
Gene Symbol UCK1
SynonymsURK1;
Alternate namesuridine-cytidine kinase 1; UCK 1; cytidine monophosphokinase 1; uridine monophosphokinase 1;
Chromosome9
Map Location9q34.13
EC Number2.7.1.48
SummaryThis gene encodes a uridine-cytidine kinase that catalyzes the phosphorylation of uridine and cytidine to uridine monophosphate (UMP) and cytidine monophosphate (CMP) but not the phosphorylation of deoxyribonucleosides or purine ribonucleosides. This enzyme can also phosphorylate uridine and cytidine analogs and uses both ATP and GTP as a phosphate donor. Alternative splicing results in multiple splice variants encoding distinct isoforms. [provided by RefSeq, May 2012]
OrthologsView orthologs and multiple alignments for UCK1

Proteins

uridine-cytidine kinase 1 isoform a
Refseq ID:NP_113620
Protein GI:13899253
UniProt ID:Q9HA47
mRNA ID:NM_031432
Length:277
RefSeq Status:
MASAGGEDCESPAPEADRPHQRPFLIGVSGGTASGKSTVCEKIMELLGQNEVEQRQRKVVILSQDRFYKVLTAEQKAKALKGQYNFDHPDAFDNDLMHRT
LKNIVEGKTVEVPTYDFVTHSRLPETTVVYPADVVLFEGILVFYSQEIRDMFHLRLFVDTDSDVRLSRRVLRDVRRGRDLEQILTQYTTFVKPAFEEFCL
PTKKYADVIIPRGVDNMVAINLIVQHIQDILNGDICKWHRGGSNGRSYKRTFSEPGDHPGMLTSGKRSHLESSSRPH
 
uridine-cytidine kinase 1 isoform b
Refseq ID:NP_001129426
Protein GI:209863022
UniProt ID:Q9HA47
mRNA ID:NM_001135954
Length:201
RefSeq Status:
MASAGGEDCESPAPEADRPHQRPFLIGVSGGTASGKSTVCEKIMELLGQNEVEQRQRKVVILSQDRFYKVLTAEQKAKALKGQYNFDHPDAFDNDLMHRT
LKNIVEGKTVEVPTYDFVTHSRLPETTVVYPADVVLFEGILVFYSQEIRDMFHLRLFVDTDSDVRLSRRDKEVCRCDHPARSGQYGCHQPDRAAHPGHSE
W
 
uridine-cytidine kinase 1 isoform c
Refseq ID:NP_001248379
Protein GI:387598085
UniProt ID:Q9HA47
mRNA ID:NM_001261450
Length:268
RefSeq Status:
MASAGGEDCESPAPEADRPHQRPFLIGSTVCEKIMELLGQNEVEQRQRKVVILSQDRFYKVLTAEQKAKALKGQYNFDHPDAFDNDLMHRTLKNIVEGKT
VEVPTYDFVTHSRLPETTVVYPADVVLFEGILVFYSQEIRDMFHLRLFVDTDSDVRLSRRVLRDVRRGRDLEQILTQYTTFVKPAFEEFCLPTKKYADVI
IPRGVDNMVAINLIVQHIQDILNGDICKWHRGGSNGRSYKRTFSEPGDHPGMLTSGKRSHLESSSRPH
 
uridine-cytidine kinase 1 isoform d
Refseq ID:NP_001248380
Protein GI:387598087
UniProt ID:Q9HA47
mRNA ID:NM_001261451
Length:282
RefSeq Status:
MASAGGEDCESPAPEADRPHQRPFLIGDERFQAGIPLLCLQSTVCEKIMELLGQNEVEQRQRKVVILSQDRFYKVLTAEQKAKALKGQYNFDHPDAFDND
LMHRTLKNIVEGKTVEVPTYDFVTHSRLPETTVVYPADVVLFEGILVFYSQEIRDMFHLRLFVDTDSDVRLSRRVLRDVRRGRDLEQILTQYTTFVKPAF
EEFCLPTKKYADVIIPRGVDNMVAINLIVQHIQDILNGDICKWHRGGSNGRSYKRTFSEPGDHPGMLTSGKRSHLESSSRPH
 
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