Summary of Study ST001172

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000784. The data can be accessed directly via it's Project DOI: 10.21228/M8BH6F This work is supported by NIH grant, U2C- DK119886.

See: https://www.metabolomicsworkbench.org/about/howtocite.php

This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.

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Study IDST001172
Study TitleDeep Metabolomics of a High-Grade Serous Ovarian Cancer Triple Knockout Mouse Model.
Study TypeUntargeted metabolomics
Study SummaryMetabolic alternations were investigated by applying Ultra Performance Liquid Chromatography Mass Spectrometry (UPLC-MS) to serum samples collected from triple knockout (TKO) mice at pre-malignant, early, and advanced stages of HGSC. Samples were analyzed with control mice, which have the same genetic background as TKO mice but develop no tumors. To enhance the selectivity for HGSC-specific metabolite markers, a tumor control group was also included. These were uterine tumor (UT) mice that developed uterine tumors, but no HGSC. All samples were analyzed using reverse phase (RP) and hydrophilic interaction liquid chromatography (HILIC) UPLC-MS analysis in positive and negative ion modes.
Institute
Georgia Institute of Technology
DepartmentChemistry
LaboratoryFernández
Last NameHuang
First NameDanning
Address901 Atlantic Dr NE
Emaildhuang74@gatech.edu
Phone4045127523
Submit Date2019-04-16
Num Groups5
Total Subjects84
Num Females84
Raw Data AvailableYes
Raw Data File Type(s)raw(Thermo)
Analysis Type DetailLC-MS
Release Date2019-10-11
Release Version1
Danning Huang Danning Huang
https://dx.doi.org/10.21228/M8BH6F
ftp://www.metabolomicsworkbench.org/Studies/ application/zip

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Factors:

Subject type: Mammal; Subject species: Mus musculus (Factor headings shown in green)

mb_sample_id local_sample_id Group
SA08123938ctrl
SA08124028ctrl
SA08124129ctrl
SA08124230ctrl
SA08124327ctrl
SA08124426ctrl
SA08124523ctrl
SA08124624ctrl
SA08124725ctrl
SA08124841ctrl
SA08124931ctrl
SA08125037ctrl
SA08125139ctrl
SA08125240ctrl
SA08125332ctrl
SA08125436ctrl
SA08125533ctrl
SA08125634ctrl
SA08125735ctrl
SA08119646ET
SA08119745ET
SA08119844ET
SA08119947ET
SA08120049ET
SA08120151ET
SA08120250ET
SA08120342ET
SA08120448ET
SA08120543ET
SA08120656LT
SA08120755LT
SA08120857LT
SA08120959LT
SA08121060LT
SA08121154LT
SA08121253LT
SA08121365LT
SA08121467LT
SA08121566LT
SA08121652LT
SA08121761LT
SA08121858LT
SA08121962LT
SA08122063LT
SA08122164LT
SA0812582pre
SA0812596pre
SA08126018pre
SA08126119pre
SA08126220pre
SA08126321pre
SA08126417pre
SA08126516pre
SA08126613pre
SA08126714pre
SA08126815pre
SA08126922pre
SA08127011pre
SA08127112pre
SA0812725pre
SA0812734pre
SA0812747pre
SA0812758pre
SA0812761pre
SA08127710pre
SA0812789pre
SA0812793pre
SA08122269UT
SA08122368UT
SA08122470UT
SA08122571UT
SA08122673UT
SA08122774UT
SA08122875UT
SA08122984UT
SA08123082UT
SA08123177UT
SA08123272UT
SA08123376UT
SA08123478UT
SA08123579UT
SA08123681UT
SA08123780UT
SA08123883UT
Showing results 1 to 84 of 84
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