Summary of Study ST001211
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000814. The data can be accessed directly via it's Project DOI: 10.21228/M8G40M This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.
| Study ID | ST001211 |
| Study Title | Metabolomic Markers of Methotrexate Response, In Vitro |
| Study Summary | Erythroblastoid cells (K562) maintained in logarithmic growth phase were treated with 1000 nM methotrexate or vehicle alone (i.e. D-PBS) under standard culture conditions for 24 hours. Cellular response to methotrexate was measured based on anti-proliferative activity by cell counting. Cells were washed, flash frozen in liquid nitrogen and submitted for metabolomics analysis to the NIH West Coast Metabolomics Center. |
| Institute | University of Kansas |
| Department | Pharmacy Practice |
| Laboratory | Funk Lab |
| Last Name | Funk |
| First Name | Ryan |
| Address | 2106 Olathe Boulevard |
| ryanfunk@kumc.edu | |
| Phone | 9135885000 |
| Submit Date | 2019-07-03 |
| Num Groups | 2 |
| Total Subjects | 20 samples |
| Analysis Type Detail | GC-MS/LC-MS |
| Release Date | 2020-01-06 |
| Release Version | 1 |
Select appropriate tab below to view additional metadata details:
Factors:
Subject type: Cultured cells; Subject species: Homo sapiens (Factor headings shown in green)
| mb_sample_id | local_sample_id | Group |
|---|---|---|
| SA085210 | 9 | Control |
| SA085211 | 10 | Control |
| SA085212 | 1 | Control |
| SA085213 | 7 | Control |
| SA085214 | 8 | Control |
| SA085215 | 6 | Control |
| SA085216 | 2 | Control |
| SA085217 | 4 | Control |
| SA085218 | 3 | Control |
| SA085219 | 5 | Control |
| SA085220 | 18 | Methotrexate |
| SA085221 | 19 | Methotrexate |
| SA085222 | 20 | Methotrexate |
| SA085223 | 17 | Methotrexate |
| SA085224 | 11 | Methotrexate |
| SA085225 | 12 | Methotrexate |
| SA085226 | 13 | Methotrexate |
| SA085227 | 14 | Methotrexate |
| SA085228 | 15 | Methotrexate |
| SA085229 | 16 | Methotrexate |
| Showing results 1 to 20 of 20 |
