Summary of Study ST002606

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001020. The data can be accessed directly via it's Project DOI: 10.21228/M8V97D This work is supported by NIH grant, U2C- DK119886.

See: https://www.metabolomicsworkbench.org/about/howtocite.php

This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.

Study ID	ST002606
Study Title	MoTrPAC: Endurance exercise training study in young adult rats, Tissue:Kidney - Targeted Oxylipins
Study Summary	The goal of the endurance exercise training study in young adult rats (internal code: PASS1B-06) was to perform exercise training studies in adult (6 month) F344 rats, and from these rats collect as many tissues as feasible in order to provide high quality samples for detailed analysis by chemical analysis sites. Tissues were collected from 10-12 rats sedentary control rats concurrent with the collection of the 8-week training groups. The 8-week training group and controls were from the same cohort and same age at euthanasia (either 8). For the older age group, an additional set of controls (n=5-6) were collected with the 1-2 week training group. Rats were either sedentary or underwent an exercise training program. Rats were exercised on the rodent treadmill 5 days per week using a progressive training protocol designed to exercise the rats at approximately 70% of VO2max as outlined in the Table on the next page. Training was performed no earlier than 10:00 am and no later than 5:00 pm over 5 consecutive days per week. Training was initiated with the treadmill set at 70% of VO2 max (see tables) and 5 degrees grade for 20 minutes. The duration of exercise was increased by one minute each day until day 31 of training (start of week 7), when a duration of 50 min was reached. Speed and grade of each training session increased in larger increments due to treadmill parameters. The highest intensity and duration of training began on day 31. This intensity was maintained for the final 10 days of the protocol to ensure steady state had been achieved. If any rats were unable to perform at least 4 days of training per week they were removed from the study and euthanized. It is important to note that the starting treadmill speed varied depending on the sex and age of the rat. The initial and maximum speeds were based on VO2max measurements obtained during the pre-training testing of the compliant rats. Rats assigned to the control group followed a schedule similar to the training group. They were placed in one lane on the treadmill for 15 minutes/day, 5 days per week. The treadmill was set at 0 m/min at an incline that corresponded to the incline being used by the training group.
Institute	Emory University
Department	Biochemistry
Laboratory	Integrated Lipidomics and Metabolomics Core
Last Name	Ortlund
First Name	Eric
Address	1510 Clifton Rd. NE, Room G235, Atlanta, GA 30322
Email	eortlun@emory.edu
Phone	(404) 727-5014
Submit Date	2022-12-03
Raw Data Available	Yes
Raw Data File Type(s)	TBD
Analysis Type Detail	LC-MS
Release Date	2023-10-06
Release Version	1

Select appropriate tab below to view additional metadata details:

Factors:

Subject type: Mammal; Subject species: Rattus norvegicus (Factor headings shown in green)

mb_sample_id	local_sample_id	Group	Timepoint	Sex
SA260398	90252015908	Control	8 weeks of training or control time	Female
SA260399	90248015908	Control	8 weeks of training or control time	Female
SA260400	90266015908	Control	8 weeks of training or control time	Female
SA260401	90265015908	Control	8 weeks of training or control time	Female
SA260402	90245015908	Control	8 weeks of training or control time	Female
SA260403	90239015908	Control	8 weeks of training or control time	Male
SA260404	90229015908	Control	8 weeks of training or control time	Male
SA260405	90237015908	Control	8 weeks of training or control time	Male
SA260406	90232015908	Control	8 weeks of training or control time	Male
SA260407	90217015908	Control	8 weeks of training or control time	Male
SA260408	QC_blank_65	QC-Blank	0 hour	-
SA260409	QC_blank_4	QC-Blank	0 hour	-
SA260410	QC_blank_68	QC-Blank	0 hour	-
SA260411	QC_blank_69	QC-Blank	0 hour	-
SA260412	QC_Standard_74	QC-ExternalStandard	0 hour	-
SA260413	QC_Standard_75	QC-ExternalStandard	0 hour	-
SA260414	QC_Standard_73	QC-ExternalStandard	0 hour	-
SA260415	QC_Standard_72	QC-ExternalStandard	0 hour	-
SA260416	QC_Standard_70	QC-ExternalStandard	0 hour	-
SA260417	QC_Standard_71	QC-ExternalStandard	0 hour	-
SA260418	QC_Standard_76	QC-ExternalStandard	0 hour	-
SA260419	QC_Standard_77	QC-ExternalStandard	0 hour	-
SA260420	QC_40	QC-Pooled	0 hour	-
SA260421	QC_51	QC-Pooled	0 hour	-
SA260422	QC_62	QC-Pooled	0 hour	-
SA260423	QC_66	QC-Pooled	0 hour	-
SA260424	QC_29	QC-Pooled	0 hour	-
SA260425	QC_7	QC-Pooled	0 hour	-
SA260426	QC_18	QC-Pooled	0 hour	-
SA260427	QC_prerun_1	QC-PreRun	0 hour	-
SA260428	QC_prerun_2	QC-PreRun	0 hour	-
SA260429	QC_prerun_3	QC-PreRun	0 hour	-
SA260430	QC_SRM	QC-Reference	0 hour	-
SA260431	G_QC_1_63	QC-Reference	0 hour	-
SA260432	G_QC_2_6	QC-Reference	0 hour	-
SA260433	G_QC_1_5	QC-Reference	0 hour	-
SA260434	G_QC_2_64	QC-Reference	0 hour	-
SA260435	90560015908	Training	1 week of training or control time	Female
SA260436	90564015908	Training	1 week of training or control time	Female
SA260437	90567015908	Training	1 week of training or control time	Female
SA260438	90559015908	Training	1 week of training or control time	Female
SA260439	90571015908	Training	1 week of training or control time	Female
SA260440	90422015908	Training	1 week of training or control time	Male
SA260441	90430015908	Training	1 week of training or control time	Male
SA260442	90421015908	Training	1 week of training or control time	Male
SA260443	90423015908	Training	1 week of training or control time	Male
SA260444	90426015908	Training	1 week of training or control time	Male
SA260445	90585015908	Training	2 weeks of training	Female
SA260446	90581015908	Training	2 weeks of training	Female
SA260447	90578015908	Training	2 weeks of training	Female
SA260448	90576015908	Training	2 weeks of training	Female
SA260449	90587015908	Training	2 weeks of training	Female
SA260450	90444015908	Training	2 weeks of training	Male
SA260451	90439015908	Training	2 weeks of training	Male
SA260452	90449015908	Training	2 weeks of training	Male
SA260453	90450015908	Training	2 weeks of training	Male
SA260454	90441015908	Training	2 weeks of training	Male
SA260455	90412015908	Training	4 weeks of training	Female
SA260456	90420015908	Training	4 weeks of training	Female
SA260457	90406015908	Training	4 weeks of training	Female
SA260458	90410015908	Training	4 weeks of training	Female
SA260459	90416015908	Training	4 weeks of training	Female
SA260460	90281015908	Training	4 weeks of training	Male
SA260461	90280015908	Training	4 weeks of training	Male
SA260462	90292015908	Training	4 weeks of training	Male
SA260463	90283015908	Training	4 weeks of training	Male
SA260464	90289015908	Training	4 weeks of training	Male
SA260465	90254015908	Training	8 weeks of training or control time	Female
SA260466	90251015908	Training	8 weeks of training or control time	Female
SA260467	90267015908	Training	8 weeks of training or control time	Female
SA260468	90259015908	Training	8 weeks of training or control time	Female
SA260469	90258015908	Training	8 weeks of training or control time	Female
SA260470	90223015908	Training	8 weeks of training or control time	Male
SA260471	90222015908	Training	8 weeks of training or control time	Male
SA260472	90225015908	Training	8 weeks of training or control time	Male
SA260473	90227015908	Training	8 weeks of training or control time	Male
SA260474	90218015908	Training	8 weeks of training or control time	Male

Showing results 1 to 77 of 77

Showing results 1 to 77 of 77