Summary of Study ST002651

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001020. The data can be accessed directly via it's Project DOI: 10.21228/M8V97D This work is supported by NIH grant, U2C- DK119886.

See: https://www.metabolomicsworkbench.org/about/howtocite.php

This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.

Study ID	ST002651
Study Title	MoTrPAC: Endurance exercise training study in young adult rats, Tissue:Heart - Untargeted Lipidomics, Reversed-Phase Negative
Study Summary	The goal of the endurance exercise training study in young adult rats (internal code: PASS1B-06) was to perform exercise training studies in adult (6 month) F344 rats, and from these rats collect as many tissues as feasible in order to provide high quality samples for detailed analysis by chemical analysis sites. Tissues were collected from 10-12 rats sedentary control rats concurrent with the collection of the 8-week training groups. The 8-week training group and controls were from the same cohort and same age at euthanasia (either 8). For the older age group, an additional set of controls (n=5-6) were collected with the 1-2 week training group. Rats were either sedentary or underwent an exercise training program. Rats were exercised on the rodent treadmill 5 days per week using a progressive training protocol designed to exercise the rats at approximately 70% of VO2max as outlined in the Table on the next page. Training was performed no earlier than 10:00 am and no later than 5:00 pm over 5 consecutive days per week. Training was initiated with the treadmill set at 70% of VO2 max (see tables) and 5 degrees grade for 20 minutes. The duration of exercise was increased by one minute each day until day 31 of training (start of week 7), when a duration of 50 min was reached. Speed and grade of each training session increased in larger increments due to treadmill parameters. The highest intensity and duration of training began on day 31. This intensity was maintained for the final 10 days of the protocol to ensure steady state had been achieved. If any rats were unable to perform at least 4 days of training per week they were removed from the study and euthanized. It is important to note that the starting treadmill speed varied depending on the sex and age of the rat. The initial and maximum speeds were based on VO2max measurements obtained during the pre-training testing of the compliant rats. Rats assigned to the control group followed a schedule similar to the training group. They were placed in one lane on the treadmill for 15 minutes/day, 5 days per week. The treadmill was set at 0 m/min at an incline that corresponded to the incline being used by the training group.
Institute	Georgia Institute of Technology
Department	Department of Chemistry and Biochemistry
Laboratory	Systems Mass Spectrometry Core (SyMSC)
Last Name	Facundo
First Name	Fernandez
Address	901 Atlantic Dr NW, Atlanta, GA 30332-0400
Email	facundo.fernandez@chemistry.gatech.edu
Phone	(404) 385-4432
Submit Date	2023-05-01
Raw Data Available	Yes
Raw Data File Type(s)	TBD
Analysis Type Detail	LC-MS
Release Date	2023-10-06
Release Version	1

Select appropriate tab below to view additional metadata details:

Factors:

Subject type: Mammal; Subject species: Rattus norvegicus (Factor headings shown in green)

mb_sample_id	local_sample_id	Group	Timepoint	Sex
SA263427	90245015808	Control	8 weeks of training or control time	Female
SA263428	90266015808	Control	8 weeks of training or control time	Female
SA263429	90252015808	Control	8 weeks of training or control time	Female
SA263430	90248015808	Control	8 weeks of training or control time	Female
SA263431	90265015808	Control	8 weeks of training or control time	Female
SA263432	90239015808	Control	8 weeks of training or control time	Male
SA263433	90232015808	Control	8 weeks of training or control time	Male
SA263434	90237015808	Control	8 weeks of training or control time	Male
SA263435	90229015808	Control	8 weeks of training or control time	Male
SA263436	90217015808	Control	8 weeks of training or control time	Male
SA263437	SampleBlank05	QC-Blank	0 hour	-
SA263438	SampleBlank03	QC-Blank	0 hour	-
SA263439	SampleBlank02	QC-Blank	0 hour	-
SA263440	SampleBlank04	QC-Blank	0 hour	-
SA263441	SampleBlank06	QC-Blank	0 hour	-
SA263442	SampleBlank01	QC-Blank	0 hour	-
SA263443	QC07	QC-Pooled	0 hour	-
SA263444	QC06	QC-Pooled	0 hour	-
SA263445	QC05	QC-Pooled	0 hour	-
SA263446	QC01	QC-Pooled	0 hour	-
SA263447	QC02	QC-Pooled	0 hour	-
SA263448	QC08	QC-Pooled	0 hour	-
SA263449	QC04	QC-Pooled	0 hour	-
SA263450	QC03	QC-Pooled	0 hour	-
SA263451	IPE_Reference_Heart02	QC-Reference	0 hour	-
SA263452	IPE_Reference_Heart	QC-Reference	0 hour	-
SA263453	SED_Reference_Heart	QC-Reference	0 hour	-
SA263454	SED_Reference_Heart02	QC-Reference	0 hour	-
SA263455	90567015808	Training	1 week of training or control time	Female
SA263456	90560015808	Training	1 week of training or control time	Female
SA263457	90564015808	Training	1 week of training or control time	Female
SA263458	90559015808	Training	1 week of training or control time	Female
SA263459	90571015808	Training	1 week of training or control time	Female
SA263460	90423015808	Training	1 week of training or control time	Male
SA263461	90421015808	Training	1 week of training or control time	Male
SA263462	90426015808	Training	1 week of training or control time	Male
SA263463	90422015808	Training	1 week of training or control time	Male
SA263464	90430015808	Training	1 week of training or control time	Male
SA263465	90585015808	Training	2 weeks of training	Female
SA263466	90578015808	Training	2 weeks of training	Female
SA263467	90576015808	Training	2 weeks of training	Female
SA263468	90587015808	Training	2 weeks of training	Female
SA263469	90581015808	Training	2 weeks of training	Female
SA263470	90450015808	Training	2 weeks of training	Male
SA263471	90439015808	Training	2 weeks of training	Male
SA263472	90441015808	Training	2 weeks of training	Male
SA263473	90444015808	Training	2 weeks of training	Male
SA263474	90449015808	Training	2 weeks of training	Male
SA263475	90412015808	Training	4 weeks of training	Female
SA263476	90410015808	Training	4 weeks of training	Female
SA263477	90420015808	Training	4 weeks of training	Female
SA263478	90416015808	Training	4 weeks of training	Female
SA263479	90406015808	Training	4 weeks of training	Female
SA263480	90280015808	Training	4 weeks of training	Male
SA263481	90292015808	Training	4 weeks of training	Male
SA263482	90283015808	Training	4 weeks of training	Male
SA263483	90289015808	Training	4 weeks of training	Male
SA263484	90281015808	Training	4 weeks of training	Male
SA263485	90251015808	Training	8 weeks of training or control time	Female
SA263486	90254015808	Training	8 weeks of training or control time	Female
SA263487	90267015808	Training	8 weeks of training or control time	Female
SA263488	90259015808	Training	8 weeks of training or control time	Female
SA263489	90258015808	Training	8 weeks of training or control time	Female
SA263490	90218015808	Training	8 weeks of training or control time	Male
SA263491	90225015808	Training	8 weeks of training or control time	Male
SA263492	90227015808	Training	8 weeks of training or control time	Male
SA263493	90222015808	Training	8 weeks of training or control time	Male
SA263494	90223015808	Training	8 weeks of training or control time	Male

Showing results 1 to 68 of 68

Showing results 1 to 68 of 68