Summary of Study ST002943
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001830. The data can be accessed directly via it's Project DOI: 10.21228/M85H91 This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
| Study ID | ST002943 |
| Study Title | Targeted bile acid analysis for the XMaS trial. |
| Study Summary | The Xanthohumol microbiome and signature (XMaS) study in healthy adults was a phase I, triple-masked, placebo-controlled clinical trial in healthy adults investigating effects of a natural product supplement of gut microbiome composition and metabolism. Xanthohumol, a flavonoid from the hops plant or placebo was administered to 27 healthy adults daily for eight weeks. Fecal, plasma, and 24-hr urine collections were obtained from participants at baseline and 2-week intervals. The main objective of this study was to quantify fecal bile acids from participants from the XMaS study. |
| Institute | Oregon State University |
| Last Name | Jamieson |
| First Name | Paige |
| Address | 307 LINUS PAULING SCIENCE CTR |
| jamiesop@oregonstate.edu | |
| Phone | 5417379804 |
| Submit Date | 2023-10-23 |
| Analysis Type Detail | LC-MS |
| Release Date | 2024-01-01 |
| Release Version | 1 |
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Sample Preparation:
| Sampleprep ID: | SP003062 |
| Sampleprep Summary: | Fecal samples were dried using vacuum desiccator and 70% methanol:water (1:4 w/v) was added for fecal homogenate. Samples were centrifuged and supernatant was collected. 10 uL of fecal supernatant, 10 uL of cholic acid-D4 internal standard (1 ug/mL in ethanol) and 80 uL of 50% methanol:water were mixed and added to a autosampler vial. |
