Summary of Study ST000617
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000451. The data can be accessed directly via it's Project DOI: 10.21228/M8RP6W This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
| Study ID | ST000617 |
| Study Title | Validation of the application of targeted metabolomic appraoch in the diagnosis of CFS |
| Study Type | Plasma metabolomic profiling |
| Study Summary | This study was to validate the utility of the developed targeted metabolomic method in the diagnosis of chronic fatigue syndrome (CFS). Clinical validation consisted of a cohort of 20 male CFS (53 ± 2.8 years old, mean ± SEM, range 21-67 y) and 18 male controls (53 ± 3.5 years old, mean ± SEM, range 23-69 y), who were enrolled in a previous study (Naviaux et al. 2016). These plasma samples were stored in -80 ºC for about 1.5 years and reanalyzed on a different LC-MS/MS system by a different investigator. |
| Institute | University of California, San Diego |
| Department | Department of Medicine |
| Laboratory | The Mitochondrial and Metabolic Disease Center |
| Last Name | Naviaux |
| First Name | Robert |
| Address | 214 Dikinson Street, CTF-C102, San Diego, CA, 92103 |
| rnaviaux@ucsd.edu | |
| Phone | 619-993-2904 |
| Submit Date | 2017-05-17 |
| Num Groups | 2 |
| Total Subjects | 38 |
| Num Males | 38 |
| Study Comments | These plasma samples were stored in -80 ºC for about 1.5 years and reanalyzed on a different LC-MS/MS system by a different investigator. |
| Raw Data File Type(s) | wiff |
| Analysis Type Detail | LC-MS |
| Release Date | 2017-06-17 |
| Release Version | 1 |
Select appropriate tab below to view additional metadata details:
Combined analysis:
| Analysis ID | AN000946 | AN000947 |
|---|---|---|
| Chromatography ID | CH000674 | CH000674 |
| MS ID | MS000842 | MS000843 |
| Analysis type | MS | MS |
| Chromatography type | HILIC | HILIC |
| Chromatography system | Shimadzu 20AD | Shimadzu 20AD |
| Column | Shodex NH2P-40 2E (250× 2.0 mm) | Shodex NH2P-40 2E (250× 2.0 mm) |
| MS Type | ESI | ESI |
| MS instrument type | Triple quadrupole | Triple quadrupole |
| MS instrument name | ABI Sciex 5500 QTrap | ABI Sciex 5500 QTrap |
| Ion Mode | NEGATIVE | POSITIVE |
| Units | AUC | AUC |