Summary of Study ST000617

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench,, where it has been assigned Project ID PR000451. The data can be accessed directly via it's Project DOI: 10.21228/M8RP6W This work is supported by NIH grant, U2C- DK119886.


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Study IDST000617
Study TitleValidation of the application of targeted metabolomic appraoch in the diagnosis of CFS
Study TypePlasma metabolomic profiling
Study SummaryThis study was to validate the utility of the developed targeted metabolomic method in the diagnosis of chronic fatigue syndrome (CFS). Clinical validation consisted of a cohort of 20 male CFS (53 ± 2.8 years old, mean ± SEM, range 21-67 y) and 18 male controls (53 ± 3.5 years old, mean ± SEM, range 23-69 y), who were enrolled in a previous study (Naviaux et al. 2016). These plasma samples were stored in -80 ºC for about 1.5 years and reanalyzed on a different LC-MS/MS system by a different investigator.
University of California, San Diego
DepartmentDepartment of Medicine
LaboratoryThe Mitochondrial and Metabolic Disease Center
Last NameNaviaux
First NameRobert
Address214 Dikinson Street, CTF-C102, San Diego, CA, 92103
Submit Date2017-05-17
Num Groups2
Total Subjects38
Num Males38
Study CommentsThese plasma samples were stored in -80 ºC for about 1.5 years and reanalyzed on a different LC-MS/MS system by a different investigator.
Raw Data File Type(s)wiff
Analysis Type DetailLC-MS
Release Date2017-06-17
Release Version1
Robert Naviaux Robert Naviaux application/zip

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Project ID:PR000451
Project DOI:doi: 10.21228/M8RP6W
Project Title:Clinical validation for the utility of targeted metabolomic method in chronic fatigue syndrome
Project Type:Plasma samples
Project Summary:Chronic fatigue syndrome (CFS) is a complex, multisystem disease that has affected more than 2 million people in the United States. No biochemical diagnostic lab test is currently available.As a practical test of the reproducibility of our new metabolomic method, we reanalyzed 40 samples from an earlier CFS study
Institute:University of California, San Diego
Department:Department of Medicine
Last Name:Naviaux
First Name:Robert
Address:214 Dickinson St., Bldg CTF, Rm C102, San Diego, CA, 92103, USA