Summary of Study ST002197
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001400. The data can be accessed directly via it's Project DOI: 10.21228/M8RM5T This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.
Study ID | ST002197 |
Study Title | Metabolic signature of C-protein induced myositis mouse model |
Study Summary | Objective of this study was to find Metabolic signature of C-protein induced myositis mouse model. For metabolite quantification, we used the tissue samples of C-protein induced myositis mouse model and control. Biocrates p180 kit enables to quantify 188 metabolites including amino acids, biogenic amines, acylcarnitine, glycerophospholipid and sugar. Significant metabolites were selected by t-test with false discovery rate p-value less than 0.05. In mouse tissue sample, a total of 68 metabolites significantly changed in CIM mice. We did pathway analysis to find altered pathway in muscle tissue. Metabolites from polyamine and beta-alanine pathway were altered. |
Institute | Seoul National University |
Last Name | Kang |
First Name | Jihyun |
Address | 502ho Intergrative Biomedical Education Research Building, 101 Deahakro, Jongro-gu, Seoul, 03080, Korea, South Korea |
jikang@snu.ac.kr | |
Phone | +821071014069 |
Submit Date | 2022-06-15 |
Raw Data Available | Yes |
Raw Data File Type(s) | wiff |
Analysis Type Detail | LC-MS |
Release Date | 2022-07-14 |
Release Version | 1 |
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Combined analysis:
Analysis ID | AN003596 |
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Analysis type | MS |
Chromatography type | Reversed phase |
Chromatography system | AB SCIEX QTRAP 5500 |
Column | Waters ACQUITY UPLC BEH C18 (75 x 2.1mm,1.7um) |
MS Type | ESI |
MS instrument type | QTRAP |
MS instrument name | ABI Sciex 5500 QTrap |
Ion Mode | POSITIVE |
Units | ng/mL |
Chromatography:
Chromatography ID: | CH002657 |
Instrument Name: | AB SCIEX QTRAP 5500 |
Column Name: | Waters ACQUITY UPLC BEH C18 (75 x 2.1mm,1.7um) |
Solvent A: | 100% water; 0.2% formic acid |
Solvent B: | 100% acetonitrile; 0.2% formic acid |
Chromatography Type: | Reversed phase |