Summary of Study ST001795
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001139. The data can be accessed directly via it's Project DOI: 10.21228/M8GH59 This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.
Study ID | ST001795 |
Study Title | Changes in mesenteric lymph lipid profile of mice upon high-fat diet with and without Celecoxib (part I) |
Study Type | Untargeted lipidomics analysis |
Study Summary | Untargeted lipid profiling of mesenteric mice lymph from mice fed with CHOW, HFD and HFD supplemented with COx-2 inhibitor drug Celecoxib. It is proposed that Celecoxib can protect from deleterious morphological changes in lymphatic system caused by obesity/HFD. |
Institute | Monash Institute of Pharmaceutical Sciences |
Department | Drug Delivery, Disposition and Dynamics |
Laboratory | Trevaskis Lab, Creek Lab |
Last Name | Anderson |
First Name | Dovile |
Address | 6 Anderson |
dovile.anderson@gmail.com | |
Phone | 8671141 |
Submit Date | 2021-05-12 |
Num Groups | 3 |
Total Subjects | 26 |
Num Males | 26 |
Publications | Manuscript NATMETAB-A20022406A Mesenteric lymphatic dysfunction promotes insulin resistance and represents a potential novel treatment target in obesity |
Raw Data Available | Yes |
Raw Data File Type(s) | raw(Thermo) |
Analysis Type Detail | LC-MS |
Release Date | 2021-06-02 |
Release Version | 1 |
Select appropriate tab below to view additional metadata details:
Collection:
Collection ID: | CO001865 |
Collection Summary: | The efferent mesenteric lymphatic duct was cannulated in isoflurane anaesthetised non-fasted mice or rats and lymph fluid was collected for up to 4 h. For the lymphatic drug transport study, lymph was collected in mice that were fasted for 3-4 h. The mesenteric lymph duct cannulation was performed as described previously in rats4 and mice5 and mesenteric lymph fluid was collected continuously for up to 6 h. |
Sample Type: | Mesenteric lymph |
Storage Conditions: | -80℃ |