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MB Sample ID: SA113196

Local Sample ID:224_035
Subject ID:SU001464
Subject Type:Mammal
Subject Species:Sus scrofa
Taxonomy ID:9823

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Treatment ID:TR001479
Treatment Summary:Male swine (n=5) were anesthetized, mechanically ventilated, and surgically instrumented for continuous hemodynamic monitoring and serial blood sampling. Animals were inoculated with uropathogenic E. coli by direct injection into the renal parenchyma and were maintained under anesthesia for up to 24 hours. The natural history of the infection was studied, animals were not resuscitated. Multi-dimensional data were collected hourly to every 6 hours; all animals were euthanized when at predetermined physiologic endpoints.