Summary of Study ST000414
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000323. The data can be accessed directly via it's Project DOI: 10.21228/M8ZS3N This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
| Study ID | ST000414 |
| Study Title | Metabolomics-based screening of the Malaria Box reveals both novel and established mechanisms of action |
| Study Type | Drug incubation |
| Study Summary | Measuring the impact of MMV Malaria Box compounds on metabolism in Plasmodium falciparum-infected red blood cells |
| Institute | Monash Institute of Pharmaceutical Sciences |
| Department | Drug delivery, disposition and dynamics |
| Laboratory | Creek lab |
| Last Name | Creek |
| First Name | Darren |
| Address | 381 Royal Parade, Parkville, Melbourne, VIC3052, Australia |
| Darren.Creek@monash.edu | |
| Phone | N/A |
| Submit Date | 2016-06-16 |
| Num Groups | 126 |
| Total Subjects | 18 |
| Study Comments | 524 |
| Raw Data Available | Yes |
| Raw Data File Type(s) | raw(Thermo) |
| Analysis Type Detail | LC-MS |
| Release Date | 2017-07-10 |
| Release Version | 1 |
Select appropriate tab below to view additional metadata details:
Factors:
Subject type: Cells; Subject species: Plasmodium falciparum (Factor headings shown in green)
| mb_sample_id | local_sample_id | Drug |
|---|---|---|
| SA020320 | ciDGb | 2-deoxyglucose |
| SA020321 | ciDGa | 2-deoxyglucose |
| SA020322 | ciDGc | 2-deoxyglucose |
| SA020323 | ciDGd | 2-deoxyglucose |
| SA020324 | ciArt0010b | Art0010 |
| SA020325 | ciArt0010a | Art0010 |
| SA020326 | ciArt0010d | Art0010 |
| SA020327 | ciArt0010c | Art0010 |
| SA020328 | ciArt0100c | Art0100 |
| SA020329 | ciArt0100b | Art0100 |
| SA020330 | ciArt0100d | Art0100 |
| SA020331 | ciArt0100a | Art0100 |
| SA020332 | ciArt1000a | Art1000 |
| SA020333 | ciArt1000d | Art1000 |
| SA020334 | ciArt1000c | Art1000 |
| SA020335 | ciArt1000b | Art1000 |
| SA020336 | ciARd | Artemisinin |
| SA020337 | ciARc | Artemisinin |
| SA020338 | ciArtemisb | Artemisinin |
| SA020339 | ciARb | Artemisinin |
| SA020340 | ciArtemisa | Artemisinin |
| SA020341 | ciArtemisc | Artemisinin |
| SA020342 | ciARa | Artemisinin |
| SA020343 | ciArtemisd | Artemisinin |
| SA020344 | ciAtovaqnd | Atovaqn |
| SA020345 | ciAtovaqnc | Atovaqn |
| SA020346 | ciAtovaqnb | Atovaqn |
| SA020347 | ciAtovaqna | Atovaqn |
| SA020348 | ciAQa | Atovaquone |
| SA020349 | ciAQb | Atovaquone |
| SA020350 | ciAQd | Atovaquone |
| SA020351 | ciAQc | Atovaquone |
| SA020352 | Blank3 | Blank |
| SA020353 | Blank2 | Blank |
| SA020354 | blank1 | Blank |
| SA020355 | Blankrestart | Blank |
| SA020356 | Blank1_140319142833 | Blank |
| SA020357 | BMSolventd | Blank |
| SA020358 | blankstart | Blank |
| SA020359 | BMSolventb_140311064719 | Blank |
| SA020360 | bMSolventc | Blank |
| SA020361 | bMSolventb | Blank |
| SA020362 | bMSolvent | Blank |
| SA020363 | BMSolventb | Blank |
| SA020364 | ciBSb | Buthionine Sulfoxime |
| SA020365 | ciBSc | Buthionine Sulfoxime |
| SA020366 | ciBSd | Buthionine Sulfoxime |
| SA020367 | ciBSa | Buthionine Sulfoxime |
| SA020808 | ci33b | c3361 |
| SA020809 | ci33d | c3361 |
| SA020810 | ci33c | c3361 |
| SA020811 | ci33a | c3361 |
| SA020368 | ciCQc | Chloroquine |
| SA020369 | ciCQd | Chloroquine |
| SA020370 | ciCQb | Chloroquine |
| SA020371 | ciCQa | Chloroquine |
| SA020372 | ciDMb | DMSO_DF |
| SA020373 | ciDMa | DMSO_DF |
| SA020374 | ciDMc | DMSO_DF |
| SA020375 | ciDMSO_DFf | DMSO_DF |
| SA020376 | ciDMSO_DFh | DMSO_DF |
| SA020377 | ciDMSO_DFa | DMSO_DF |
| SA020378 | ciDMd | DMSO_DF |
| SA020379 | ciDMSO_DFc | DMSO_DF |
| SA020380 | ciDMSO_DFb | DMSO_DF |
| SA020381 | ciDMSO_DFd | DMSO_DF |
| SA020382 | ciDMSO_DFe | DMSO_DF |
| SA020383 | ciDMSO_DFg | DMSO_DF |
| SA020384 | ciFAa | Fluoroacetate |
| SA020385 | ciFAd | Fluoroacetate |
| SA020386 | ciFAb | Fluoroacetate |
| SA020387 | ciFAc | Fluoroacetate |
| SA020388 | ciMB1_A02d | MB1_A02 |
| SA020389 | ciMB1_A02a | MB1_A02 |
| SA020390 | ciMB1_A02b | MB1_A02 |
| SA020391 | ciMB1_A02c | MB1_A02 |
| SA020392 | ciMB1_A03c | MB1_A03 |
| SA020393 | ciMB1_A03b | MB1_A03 |
| SA020394 | ciMB1_A03a | MB1_A03 |
| SA020395 | ciMB1_A03d | MB1_A03 |
| SA020396 | ciMB1_A04a | MB1_A04 |
| SA020397 | ciMB1_A04c | MB1_A04 |
| SA020398 | ciMB1_A04b | MB1_A04 |
| SA020399 | ciMB1_A04d | MB1_A04 |
| SA020400 | ciMB1_A05b | MB1_A05 |
| SA020401 | ciMB1_A05d | MB1_A05 |
| SA020402 | ciMB1_A05a | MB1_A05 |
| SA020403 | ciMB1_A05c | MB1_A05 |
| SA020404 | ciMB1_A06c | MB1_A06 |
| SA020405 | ciMB1_A06a | MB1_A06 |
| SA020406 | ciMB1_A06d | MB1_A06 |
| SA020407 | ciMB1_A06b | MB1_A06 |
| SA020408 | ciMB1_A07b | MB1_A07 |
| SA020409 | ciMB1_A07d | MB1_A07 |
| SA020410 | ciMB1_A07c | MB1_A07 |
| SA020411 | ciMB1_A07a | MB1_A07 |
| SA020412 | ciMB1_A08c | MB1_A08 |
| SA020413 | ciMB1_A08d | MB1_A08 |
| SA020414 | ciMB1_A08a | MB1_A08 |
| SA020415 | ciMB1_A08b | MB1_A08 |
