Summary of Study ST002477

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001600. The data can be accessed directly via it's Project DOI: 10.21228/M8W70C This work is supported by NIH grant, U2C- DK119886.

See: https://www.metabolomicsworkbench.org/about/howtocite.php

This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.

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Study IDST002477
Study TitleNeutrophil metabolomics in COVID-19
Study SummarySevere COVID-19 is characterized by an increase in the number and changes in the function of innate immune cells including neutrophils. However, it is not known how the metabolome of immune cells changes in COVID-19 patients or how metabolic changes may contribute to immune dysfunction. To address these questions, we analyzed the metabolome of neutrophils from patients with severe or mild COVID-19, or healthy controls. We identified widespread dysregulation of neutrophil metabolism with disease progression including in amino acid, redox, and central carbon metabolism.
Institute
UT Southwestern Medical Center
Last NameLi
First NameYafeng
Address5323 Harry Hines Blvd, Children's Research Institute, Dallas, TX, 75309, USA
Emailyafeng.li@utsouthwestern.edu
Phone4047696693
Submit Date2023-02-14
Raw Data AvailableYes
Raw Data File Type(s)mzXML, raw(Thermo)
Analysis Type DetailLC-MS
Release Date2023-02-26
Release Version1
Yafeng Li Yafeng Li
https://dx.doi.org/10.21228/M8W70C
ftp://www.metabolomicsworkbench.org/Studies/ application/zip

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Factors:

Subject type: Human; Subject species: Homo sapiens (Factor headings shown in green)

mb_sample_id local_sample_id Experimental Factors
SA247968Blank_03Blank
SA247969Blank_01Blank
SA247970Blank_02Blank
SA247971PMN_89Control
SA247972PMN_88Control
SA247973PMN_87Control
SA247974PMN_90Control
SA247975PMN_91Control
SA247976PMN_86Control
SA247977PMN_92Control
SA247978PMN_79Control
SA247979PMN_85Control
SA247980PMN_75Control
SA247981PMN_76Control
SA247982PMN_77Control
SA247983PMN_78Control
SA247984PMN_80Control
SA247985PMN_74Control
SA247986PMN_84Control
SA247987PMN_82Control
SA247988PMN_83Control
SA247989PMN_81Control
SA247990PMN_41Mild
SA247991PMN_42Mild
SA247992PMN_40Mild
SA247993PMN_46Mild
SA247994PMN_43Mild
SA247995PMN_38Mild
SA247996PMN_27Mild
SA247997PMN_28Mild
SA247998PMN_13Mild
SA247999PMN_12Mild
SA248000PMN_25Mild
SA248001PMN_22Mild
SA248002PMN_15Mild
SA248003PMN_16Mild
SA248004PMN_19Mild
SA248005PMN_21Mild
SA248006PMN_10Mild
SA248007PMN_08Mild
SA248008PMN_32Mild
SA248009PMN_29Mild
SA248010PMN_34Mild
SA248011PMN_35Mild
SA248012PMN_36Mild
SA248013PMN_02Mild
SA248014PMN_03Mild
SA248015PMN_07Mild
SA248016PMN_06Mild
SA248017PMN_05Mild
SA248018PMN_04Mild
SA248019PMN_14Mild
SA248020QC_pool_01QC
SA248021QC_pool_08QC
SA248022QC_pool_09QC
SA248023QC_pool_10QC
SA248024QC_pool_11QC
SA248025QC_pool_07QC
SA248026QC_pool_06QC
SA248027QC_pool_03QC
SA248028QC_pool_04QC
SA248029QC_pool_05QC
SA248030QC_pool_02QC
SA248031PMN_59Severe
SA248032PMN_55Severe
SA248033PMN_54Severe
SA248034PMN_56Severe
SA248035PMN_57Severe
SA248036PMN_58Severe
SA248037PMN_53Severe
SA248038PMN_52Severe
SA248039PMN_48Severe
SA248040PMN_49Severe
SA248041PMN_50Severe
SA248042PMN_51Severe
SA248043PMN_60Severe
SA248044PMN_61Severe
SA248045PMN_69Severe
SA248046PMN_68Severe
SA248047PMN_70Severe
SA248048PMN_71Severe
SA248049PMN_72Severe
SA248050PMN_67Severe
SA248051PMN_66Severe
SA248052PMN_62Severe
SA248053PMN_63Severe
SA248054PMN_64Severe
SA248055PMN_65Severe
SA248056PMN_73Severe
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