Summary of Study ST002491

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001608. The data can be accessed directly via it's Project DOI: 10.21228/M8VB03 This work is supported by NIH grant, U2C- DK119886.

See: https://www.metabolomicsworkbench.org/about/howtocite.php

This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.

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Study IDST002491
Study TitleSix tryptophan metabolites in mouse serum
Study SummaryWe establish that six tryptophan metabolites are essentially not CYP1A1 substrates and the level of these metabolite in mouse serum are not affected by a lack of CYP1A1 or any other Aryl hydrocarbon Receptor (AHR) dependent metabolic pathway expression in vivo. These results establish that tryptophan metabolites that circulate at significant levels in vivo are not subject to an autoregulatory feedback loop between the AHR and CYP1A1.
Institute
Pennsylvania State University
Last NameDong
First NameFancong
Address309 Life Sciences Building, University Park, PA 16802
Emailfxd93@psu.edu
Phone8148651415
Submit Date2023-02-22
Raw Data AvailableYes
Raw Data File Type(s)mzML
Analysis Type DetailLC-MS
Release Date2023-04-03
Release Version1
Fancong Dong Fancong Dong
https://dx.doi.org/10.21228/M8VB03
ftp://www.metabolomicsworkbench.org/Studies/ application/zip

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Factors:

Subject type: Mammal; Subject species: Mus musculus (Factor headings shown in green)

mb_sample_id local_sample_id Genotype
SA2489061_STD8-
SA2489071_STD9-
SA2489081_STD10-
SA2489091_STD7-
SA2489101_STD4-
SA2489111_STD2-
SA2489121_STD3-
SA2489132_STD1-
SA2489141_STD6-
SA2489152_STD3-
SA2489162_STD8-
SA2489172_STD9-
SA2489182_STD10-
SA2489192_STD7-
SA2489202_STD6-
SA2489211_STD1-
SA2489222_STD4-
SA2489232_STD5-
SA2489242_STD2-
SA2489251_STD5-
SA2489441_SERUM_KO4AHR-/-
SA2489451_SERUM_KO5AHR-/-
SA2489461_SERUM_KO3AHR-/-
SA2489471_SERUM_KO1AHR-/-
SA2489481_SERUM_KO6AHR-/-
SA2489491_SERUM_KO2AHR-/-
SA2489381_SERUM_HETS5AHR+/-
SA2489391_SERUM_HETS6AHR+/-
SA2489401_SERUM_HETS1AHR+/-
SA2489411_SERUM_HETS4AHR+/-
SA2489421_SERUM_HETS3AHR+/-
SA2489431_SERUM_HETS2AHR+/-
SA2489261_SERUM_WT4AHR+/+
SA2489271_SERUM_WT5AHR+/+
SA2489281_SERUM_WT3AHR+/+
SA2489291_SERUM_WT1AHR+/+
SA2489301_SERUM_WT10AHR+/+
SA2489311_SERUM_WT6AHR+/+
SA2489321_SERUM_WT2AHR+/+
SA2489331_SERUM_WT11AHR+/+
SA2489341_SERUM_WT12AHR+/+
SA2489351_SERUM_WT9AHR+/+
SA2489361_SERUM_WT7AHR+/+
SA2489371_SERUM_WT8AHR+/+
SA2489502_SERUM_C5wild type
SA2489512_SERUM_C4wild type
SA2489522_SERUM_C3wild type
SA2489532_SERUM_C2wild type
SA2489542_SERUM_C1wild type
SA2489552_SERUM_C6wild type
SA2489562_SERUM_PCB1wild type
SA2489572_SERUM_PCB5wild type
SA2489582_SERUM_PCB4wild type
SA2489592_SERUM_PCB3wild type
SA2489602_SERUM_PCB2wild type
SA2489612_SERUM_PCB6wild type
Showing results 1 to 56 of 56
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