Summary of Study ST000315

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000254. The data can be accessed directly via it's Project DOI: 10.21228/M8Z88C This work is supported by NIH grant, U2C- DK119886.

See: https://www.metabolomicsworkbench.org/about/howtocite.php

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Study IDST000315
Study TitleMetabolomics and Childhood Obesity: A Pilot and Feasibility Study With Multiple Phenotypic Anchors
Study TypeMetabolomics
Study Summary“Metabolomics” is a powerful new analytical approach for measuring and evaluating all small and intermediate sized metabolites in a variety of tissues or samples in conditions of health and disease. The purpose of this research is to determine if “metabolomics” can be used to address several important unanswered questions about obesity in children. First we will use metabolomics to identify patterns of metabolites in blood that are unique to obese children. We will then determine if these patterns are predictive of excessive weight gain and/or poor weight loss response in non-obese and obese children enrolled in an exercise program.
Institute
University of North Carolina
DepartmentSystems and Translational Sciences
LaboratorySumner Lab
Last NameSumner
First NameSusan
AddressEastern Regional Comprehensive Metabolomics Resource Core, UNC Nutrition Research Institute, 500 Laureate Way, Kannapolis, NC, 28081
Emailsusan_sumner @unc.edu
Phone704-250-5066
Submit Date2015-12-31
Total Subjects219
Raw Data AvailableYes
Raw Data File Type(s)fid
Analysis Type DetailNMR
Release Date2016-12-31
Release Version1
Susan Sumner Susan Sumner
https://dx.doi.org/10.21228/M8Z88C
ftp://www.metabolomicsworkbench.org/Studies/ application/zip

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NMR:

NMR ID:NM000063
Analysis ID:AN000501
Instrument Name:Bruker
Instrument Type:FT-NMR
NMR Experiment Type:Other
Field Frequency Lock:Deuterium
Standard Concentration:0.5 mM
Spectrometer Frequency:700 MHz
NMR Probe:5 mm ATMA Cryoprobe
NMR Solvent:D2O
NMR Tube Size:5mm
Shimming Method:Topshim
Pulse Sequence:noesypr1d
Water Suppression:yes
Receiver Gain:4
Offset Frequency:3295.2
Chemical Shift Ref Cpd:DSS
Temperature:298.1 K
Number Of Scans:128
Dummy Scans:4
Acquisition Time:3.893
Spectral Width:12.0227 ppm, 8.417 Hz
Num Data Points Acquired:65536
Real Data Points:65536
Line Broadening:0.5 Hz
Zero Filling:yes
Apodization:Lorentzian
Baseline Correction Method:Polynomial
Chemical Shift Ref Std:DSS-D6
Binned Increment:0.04
Binned Data Excluded Range:EDTA (2.53 – 2.59 ppm, 2.68 -2.72 ppm, 3.05 – 3.28 ppm, and 3.56 – 3.66ppm); noise regions (5.40-5.68 ppm, 5.86-6.83 ppm, 7.23-7.68 ppm)
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