Summary of Study ST000930

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000644. The data can be accessed directly via it's Project DOI: 10.21228/M8F380 This work is supported by NIH grant, U2C- DK119886.

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Study IDST000930
Study TitleDefine alterations in the gut metabolome of mice infected with C. difficile
Study TypeTime course experiment
Study SummaryC57BL/6 mice were treated with antibiotics to make them susceptible to C. difficile. Mice were challenged with C. difficile and the infection was monitored for 30 hours post challenge. Mice were sacrificed at 0 hr, 12 hr, 24 hr, and 30 hr post challenge with C. difficile and gut content was collected for untargeted metabolomic analysis. The aim of this project was to define the gut metabolome throughout C. difficile infection.
Institute
North Carolina State University
DepartmentPHP
LaboratoryTheriot
Last NameTheriot
First NameCasey
Address1051 William Moore Drive
Emailcmtherio@ncsu.edu
Phone919-513-0711
Submit Date2018-02-26
Num Groups4
Total Subjects31
Num Males16
Num Females15
Analysis Type DetailLC-MS
Release Date2018-03-15
Release Version1
Casey Theriot Casey Theriot
https://dx.doi.org/10.21228/M8F380
ftp://www.metabolomicsworkbench.org/Studies/ application/zip

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Project:

Project ID:PR000644
Project DOI:doi: 10.21228/M8F380
Project Title:Alterations in the gut metabolome throughout C. difficile infection
Project Summary:C57BL/6 mice were treated with antibiotics to make them susceptible to C. difficile. Mice were challenged with C. difficile and the infection was monitored for 30 hours post challenge. Mice were sacrificed at 12 hr, 24 hr, and 30 hr post challenge with C. difficile and gut content was collected for untargeted metabolomic analysis. The aim of this project was to define the gut metabolome throughout C. difficile infection.
Institute:North Carolina State University
Department:Population Health and Pathobiology
Laboratory:Theriot
Last Name:Theriot
First Name:Casey
Address:1051 William Moore Drive, Raleigh, NC, 27607, USA
Email:cmtherio@ncsu.edu
Phone:9195130711
Funding Source:NIGMS K01 and R35
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