Summary of Study ST001909
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001203. The data can be accessed directly via it's Project DOI: 10.21228/M86Q68 This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.
| Study ID | ST001909 |
| Study Title | ATF3 regulation of serine metabolism |
| Study Type | stable isotope tracing |
| Study Summary | ATF3 is a common stress sensor, and its expression can be induced by serine deprivation. The goal of this project is to determine whether ATF3 regulates serine biosynthesis. ATF3-wildtype and –knockout cells are cultured in complete or serine-free medium supplemented with 13C-6-glucose for 24 h for stable isotope tracing. The results show that ATF3 appears to promote serine biosynthesis. |
| Institute | Augusta University |
| Last Name | Yan |
| First Name | Chunhong |
| Address | 1410 Laney Walker Blvd, Augusta, GA, 30912, USA |
| cyan@augusta.edu | |
| Phone | 7067210099 |
| Submit Date | 2021-08-11 |
| Raw Data Available | Yes |
| Raw Data File Type(s) | d |
| Analysis Type Detail | GC-MS |
| Release Date | 2021-10-02 |
| Release Version | 1 |
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Project:
| Project ID: | PR001203 |
| Project DOI: | doi: 10.21228/M86Q68 |
| Project Title: | ATF3 regulation of serine metabolism |
| Project Type: | Isotope Tracing, GC-MS |
| Project Summary: | ATF3 is a common stress sensor, and its expression can be induced by serine deprivation. The goal of this project is to determine whether ATF3 regulates serine biosynthesis. ATF3-wildtype and –knockout cells are cultured in complete or serine-free medium supplemented with 13C-6-glucose for 24 h for stable isotope tracing. The results show that ATF3 appears to promote serine biosynthesis. |
| Institute: | Augusta University |
| Department: | Georgia Cancer Center |
| Last Name: | Yan |
| First Name: | Chunhong |
| Address: | 1410 Laney Walker Blvd, Augusta, GA, 30912, USA |
| Email: | cyan@augusta.edu |
| Phone: | 7067210099 |
| Funding Source: | NIH/NCI R01CA240933, R01CA190429, R01CA236890 |
