Summary of Study ST003142
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001953. The data can be accessed directly via it's Project DOI: 10.21228/M88M77 This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.
Study ID | ST003142 |
Study Title | Effect of liver Acox1 knockout on serum lipidome in mice |
Study Summary | The liver gene expression of the peroxisomal β-oxidation enzyme acyl-coenzyme A oxidase 1 (ACOX1), which catabolizes very long chain fatty acids (VLCFA), increases in the context of obesity. To check if liver peroxisomal fatty acids beta-oxidation deficiency will affect whole body metabolic homeostasis through circulating lipids. We analyzed serum samples from 5 WT and 5 Acox1-LKO mice. |
Institute | Washington University in St. Louis |
Last Name | Lu |
First Name | Dongliang |
Address | 660 S. Euclid Ave. |
ludong-liang@wustl.edu | |
Phone | 3147476766 |
Submit Date | 2024-03-19 |
Analysis Type Detail | LC-MS |
Release Date | 2024-03-27 |
Release Version | 1 |
Select appropriate tab below to view additional metadata details:
Project:
Project ID: | PR001953 |
Project DOI: | doi: 10.21228/M88M77 |
Project Title: | Global Lipidomics of Serum Samples from control and ACOX1-LKO Mouse |
Project Summary: | In this study, we use a Acox1 liver specific knock mouse to explore the role of liver peroxisomal fatty acids beta-oxidation in whole body metabolic homeostasis. As the key enzyme of peroxisomal fatty acid beta-oxidation, knock out Acox1 in liver will affect the very long chain fatty acid accoumaltion in liver and their secretion into circulating. |
Institute: | Washington University School of Medicine |
Last Name: | Lu |
First Name: | Dongliang |
Address: | 660 S. Euclid Ave., St. Louis, Missouri, 63110, USA |
Email: | ludong-liang@wustl.edu |
Phone: | 3147476766 |