Summary of Study ST003142

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001953. The data can be accessed directly via it's Project DOI: 10.21228/M88M77 This work is supported by NIH grant, U2C- DK119886.

See: https://www.metabolomicsworkbench.org/about/howtocite.php

This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.

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Study IDST003142
Study TitleEffect of liver Acox1 knockout on serum lipidome in mice
Study SummaryThe liver gene expression of the peroxisomal β-oxidation enzyme acyl-coenzyme A oxidase 1 (ACOX1), which catabolizes very long chain fatty acids (VLCFA), increases in the context of obesity. To check if liver peroxisomal fatty acids beta-oxidation deficiency will affect whole body metabolic homeostasis through circulating lipids. We analyzed serum samples from 5 WT and 5 Acox1-LKO mice.
Institute
Washington University in St. Louis
Last NameLu
First NameDongliang
Address660 S. Euclid Ave.
Emailludong-liang@wustl.edu
Phone3147476766
Submit Date2024-03-19
Analysis Type DetailLC-MS
Release Date2024-03-27
Release Version1
Dongliang Lu Dongliang Lu
https://dx.doi.org/10.21228/M88M77
ftp://www.metabolomicsworkbench.org/Studies/ application/zip

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Treatment:

Treatment ID:TR003268
Treatment Summary:WT and Acox1-LKO mice were maintained under constant temperature (24°C), circulating air and humidity (45-65%) with 12h:12h light/dark cycle. All mice had free access to chew diet and water. 10 weeks age mice were used for analysis.
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