MGP Database

MGP003196

Ontology/Pathway Information

Entrez Gene ID	7200
Gene Name	thyrotropin-releasing hormone
Gene Symbol	TRH
Species	Homo sapiens

Gene Ontology (GO Annotations)

GO ID	Source	Type	Description
GO:0005576	TAS:Reactome	C	extracellular region
GO:0005634	IEA:Ensembl	C	nucleus
GO:0005886	IEA:Ensembl	C	plasma membrane
GO:0030141	IEA:Ensembl	C	secretory granule
GO:0008437	TAS:ProtInc	F	thyrotropin-releasing hormone activity
GO:0007628	IEA:Ensembl	P	adult walking behavior
GO:0007267	TAS:ProtInc	P	cell-cell signaling
GO:0042755	IEA:Ensembl	P	eating behavior
GO:0001692	IEA:Ensembl	P	histamine metabolic process
GO:0009755	IEA:InterPro	P	hormone-mediated signaling pathway
GO:2000252	IEA:Ensembl	P	negative regulation of feeding behavior
GO:0014050	IEA:Ensembl	P	negative regulation of glutamate secretion
GO:0014054	IEA:Ensembl	P	positive regulation of gamma-aminobutyric acid secretion
GO:0032024	IEA:Ensembl	P	positive regulation of insulin secretion
GO:0009409	IEA:Ensembl	P	response to cold
GO:0051412	IEA:Ensembl	P	response to corticosterone
GO:0045471	IEA:Ensembl	P	response to ethanol
GO:0009749	IEA:Ensembl	P	response to glucose
GO:0001666	IEA:Ensembl	P	response to hypoxia
GO:0007165	TAS:ProtInc	P	signal transduction

REACTOME Pathway Links

REACTOME Pathway ID	Description
REACT_14828	Class A/1 (Rhodopsin-like receptors)
REACT_267874	Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD)
REACT_116125	Disease
REACT_18283	G alpha (q) signalling events
REACT_120966	Gastrin-CREB signalling pathway via PKC and MAPK
REACT_19184	GPCR downstream signaling
REACT_21340	GPCR ligand binding
REACT_267615	Metabolic disorders of biological oxidation enzymes
REACT_14819	Peptide ligand-binding receptors
REACT_14797	Signaling by GPCR
REACT_111102	Signal Transduction