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MGP003337

Record overview

MGPD IDMGP003337
Gene ID7529
SpeciesHomo sapiens (Human)
Gene Nametyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
Gene Symbol YWHAB
SynonymsHS1; GW128; YWHAA; KCIP-1; HEL-S-1;
Alternate names14-3-3 protein beta/alpha; 14-3-3 alpha; brain protein 14-3-3, beta isoform; epididymis secretory protein Li 1; protein 1054; protein kinase C inhibitor protein 1; protein kinase C inhibitor protein-1; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, alpha polypeptide; tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide;
Chromosome20
Map Location20q13.1
SummaryThis gene encodes a protein belonging to the 14-3-3 family of proteins, members of which mediate signal transduction by binding to phosphoserine-containing proteins. This highly conserved protein family is found in both plants and mammals. The encoded protein has been shown to interact with RAF1 and CDC25 phosphatases, suggesting that it may play a role in linking mitogenic signaling and the cell cycle machinery. Two transcript variants, which encode the same protein, have been identified for this gene. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for YWHAB

Proteins

14-3-3 protein beta/alpha
Refseq ID:NP_647539
Protein GI:21328448
UniProt ID:P31946
mRNA ID:NM_139323
Length:246
RefSeq Status:
MTMDKSELVQKAKLAEQAERYDDMAAAMKAVTEQGHELSNEERNLLSVAYKNVVGARRSSWRVISSIEQKTERNEKKQQMGKEYREKIEAELQDICNDVL
ELLDKYLIPNATQPESKVFYLKMKGDYFRYLSEVASGDNKQTTVSNSQQAYQEAFEISKKEMQPTHPIRLGLALNFSVFYYEILNSPEKACSLAKTAFDE
AIAELDTLNEESYKDSTLIMQLLRDNLTLWTSENQGDEGDAGEGEN
 
14-3-3 protein beta/alpha
Refseq ID:NP_003395
Protein GI:4507949
UniProt ID:P31946
mRNA ID:NM_003404
Length:246
RefSeq Status:
Protein sequence is identical to GI:21328448 (mRNA isoform)
 
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