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MGP003337

Ontology/Pathway Information

Entrez Gene ID7529
Gene Nametyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta
Gene Symbol YWHAB
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005737 IDA:UniProtKBCcytoplasm
GO:0030659 TAS:ReactomeCcytoplasmic vesicle membrane
GO:0005829 TAS:ReactomeCcytosol
GO:0070062 IDA:UniProtKBCextracellular vesicular exosome
GO:0005925 IDA:UniProtKBCfocal adhesion
GO:0042470 IEA:UniProtKB-SubCellCmelanosome
GO:0016020 IDA:UniProtKBCmembrane
GO:0005634 IEA:EnsemblCnucleus
GO:0048471 IDA:UniProtKBCperinuclear region of cytoplasm
GO:0017053 IEA:EnsemblCtranscriptional repressor complex
GO:0019899 IPI:BHF-UCLFenzyme binding
GO:0042826 IPI:BHF-UCLFhistone deacetylase binding
GO:0051219 IPI:BHF-UCLFphosphoprotein binding
GO:0050815 IPI:BHF-UCLFphosphoserine binding
GO:0019904 IPI:UniProtKBFprotein domain specific binding
GO:0003714 IEA:EnsemblFtranscription corepressor activity
GO:0000186 TAS:ReactomePactivation of MAPKK activity
GO:0006915 TAS:ReactomePapoptotic process
GO:0007411 TAS:ReactomePaxon guidance
GO:0051220 IDA:BHF-UCLPcytoplasmic sequestering of protein
GO:0007173 TAS:ReactomePepidermal growth factor receptor signaling pathway
GO:0038095 TAS:ReactomePFc-epsilon receptor signaling pathway
GO:0008543 TAS:ReactomePfibroblast growth factor receptor signaling pathway
GO:0010467 TAS:ReactomePgene expression
GO:0035329 TAS:ReactomePhippo signaling
GO:0045087 TAS:ReactomePinnate immune response
GO:0008286 TAS:ReactomePinsulin receptor signaling pathway
GO:0097193 TAS:ReactomePintrinsic apoptotic signaling pathway
GO:0000165 TAS:ReactomePMAPK cascade
GO:0061024 TAS:ReactomePmembrane organization
GO:0016071 TAS:ReactomePmRNA metabolic process
GO:0035308 IDA:BHF-UCLPnegative regulation of protein dephosphorylation
GO:0045892 IEA:EnsemblPnegative regulation of transcription, DNA-templated
GO:0048011 TAS:ReactomePneurotrophin TRK receptor signaling pathway
GO:0043085 IDA:BHF-UCLPpositive regulation of catalytic activity
GO:1900740 TAS:ReactomePpositive regulation of protein insertion into mitochondrial membrane involved in apoptotic signaling pathway
GO:0051291 IEA:EnsemblPprotein heterooligomerization
GO:0006605 IEA:EnsemblPprotein targeting
GO:0007265 TAS:ReactomePRas protein signal transduction
GO:0016070 TAS:ReactomePRNA metabolic process
GO:0007264 TAS:ReactomePsmall GTPase mediated signal transduction
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_549Activation of BAD and translocation to mitochondria
REACT_697Activation of BH3-only proteins
REACT_75774Adaptive Immune System
REACT_578Apoptosis
REACT_12002ARMS-mediated activation
REACT_18266Axon guidance
REACT_24915Butyrate Response Factor 1 (BRF1) destabilizes mRNA
REACT_75790Cytokine Signaling in Immune system
REACT_147694DAP12 interactions
REACT_147814DAP12 signaling
REACT_111045Developmental Biology
REACT_116125Disease
REACT_21272Downstream signaling of activated FGFR
REACT_17025Downstream signal transduction
REACT_163936Fc epsilon receptor (FCERI) signaling
REACT_163701FCERI mediated MAPK activation
REACT_12076Frs2-mediated activation
REACT_21247FRS2-mediated cascade
REACT_120966Gastrin-CREB signalling pathway via PKC and MAPK
REACT_71Gene Expression
REACT_12606GRB2 events in EGFR signaling
REACT_115854GRB2 events in ERBB2 signaling
REACT_150210IGF1R signaling cascade
REACT_6900Immune System
REACT_6802Innate Immune System
REACT_1195Insulin receptor signalling cascade
REACT_27283Interleukin-2 signaling
REACT_964Intrinsic Pathway for Apoptosis
REACT_332IRS-mediated signalling
REACT_762IRS-related events
REACT_150203IRS-related events triggered by IGF1R
REACT_962MEK activation
REACT_11123Membrane Trafficking
REACT_18334NCAM signaling for neurite out-growth
REACT_12056NGF signalling via TRKA from the plasma membrane
REACT_268456Programmed Cell Death
REACT_12005Prolonged ERK activation events
REACT_2077RAF activation
REACT_634RAF/MAP kinase cascade
REACT_614RAF phosphorylates MEK
REACT_23898Rap1 signalling
REACT_24994Regulation of mRNA stability by proteins that bind AU-rich elements
REACT_12579SHC1 events in EGFR signaling
REACT_115993SHC1 events in ERBB2 signaling
REACT_116005SHC1 events in ERBB4 signaling
REACT_661SHC-mediated signalling
REACT_999SHC-related events
REACT_150139SHC-related events triggered by IGF1R
REACT_9417Signaling by EGFR
REACT_115871Signaling by EGFR in Cancer
REACT_268269Signaling by EGFRvIII in Cancer
REACT_115755Signaling by ERBB2
REACT_115596Signaling by ERBB4
REACT_9470Signaling by FGFR
REACT_120736Signaling by FGFR in disease
REACT_14797Signaling by GPCR
REACT_118607Signaling by Hippo
REACT_498Signaling by Insulin receptor
REACT_22232Signaling by Interleukins
REACT_169118Signaling by Leptin
REACT_268006Signaling by Ligand-Responsive EGFR Variants in Cancer
REACT_268546Signaling by Overexpressed Wild-Type EGFR in Cancer
REACT_16888Signaling by PDGF
REACT_111040Signaling by SCF-KIT
REACT_150359Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)
REACT_12529Signaling by VEGF
REACT_11061Signalling by NGF
REACT_12058Signalling to ERKs
REACT_12077Signalling to p38 via RIT and RIN
REACT_12033Signalling to RAS
REACT_111102Signal Transduction
REACT_524SOS-mediated signalling
REACT_147867Translocation of GLUT4 to the plasma membrane
REACT_25064Tristetraprolin (TTP) destabilizes mRNA
REACT_264464VEGFA-VEGFR2 Pathway
REACT_264273VEGFR2 mediated cell proliferation
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