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MGP003484

Record overview

MGPD IDMGP003484
Gene ID8317
SpeciesHomo sapiens (Human)
Gene Namecell division cycle 7
Gene Symbol CDC7
SynonymsHsk1; CDC7L1; HsCDC7; huCDC7;
Alternate namescell division cycle 7-related protein kinase; CDC7 (cell division cycle 7, S. cerevisiae, homolog)-like 1; CDC7-related kinase; cell division cycle 7 homolog; cell division cycle 7-like protein 1;
Chromosome1
Map Location1p22
EC Number2.7.11.1;
SummaryThis gene encodes a cell division cycle protein with kinase activity that is critical for the G1/S transition. The yeast homolog is also essential for initiation of DNA replication as cell division occurs. Overexpression of this gene product may be associated with neoplastic transformation for some tumors. Multiple alternatively spliced transcript variants that encode the same protein have been detected. [provided by RefSeq, Aug 2008]
OrthologsView orthologs and multiple alignments for CDC7

Proteins

cell division cycle 7-related protein kinase
Refseq ID:NP_001127891
Protein GI:197313665
UniProt ID:O00311
mRNA ID:NM_001134419
Length:574
RefSeq Status:
MEASLGIQMDEPMAFSPQRDRFQAEGSLKKNEQNFKLAGVKKDIEKLYEAVPQLSNVFKIEDKIGEGTFSSVYLATAQLQVGPEEKIALKHLIPTSHPIR
IAAELQCLTVAGGQDNVMGVKYCFRKNDHVVIAMPYLEHESFLDILNSLSFQEVREYMLNLFKALKRIHQFGIVHRDVKPSNFLYNRRLKKYALVDFGLA
QGTHDTKIELLKFVQSEAQQERCSQNKSHIITGNKIPLSGPVPKELDQQSTTKASVKRPYTNAQIQIKQGKDGKEGSVGLSVQRSVFGERNFNIHSSISH
ESPAVKLMKQSKTVDVLSRKLATKKKAISTKVMNSAVMRKTASSCPASLTCDCYATDKVCSICLSRRQQVAPRAGTPGFRAPEVLTKCPNQTTAIDMWSA
GVIFLSLLSGRYPFYKASDDLTALAQIMTIRGSRETIQAAKTFGKSILCSKEVPAQDLRKLCERLRGMDSSTPKLTSDIQGHASHQPAISEKTDHKASCL
VQTPPGQYSGNSFKKGDSNSCEHCFDEYNTNLEGWNEVPDEAYDLLDKLLDLNPASRITAEEALLHPFFKDMSL
 
cell division cycle 7-related protein kinase
Refseq ID:NP_003494
Protein GI:4502715
UniProt ID:O00311
mRNA ID:NM_003503
Length:574
RefSeq Status:
Protein sequence is identical to GI:197313665 (mRNA isoform)
 
cell division cycle 7-related protein kinase
Refseq ID:NP_001127892
Protein GI:197313667
UniProt ID:O00311
mRNA ID:NM_001134420
Length:574
RefSeq Status:
Protein sequence is identical to GI:197313665 (mRNA isoform)
 
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