MGP Database

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MGP003484

Ontology/Pathway Information

Entrez Gene ID8317
Gene Namecell division cycle 7
Gene Symbol CDC7
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005737 IDA:HGNCCcytoplasm
GO:0045171 IDA:HPACintercellular bridge
GO:0015630 IDA:HPACmicrotubule cytoskeleton
GO:0005654 IDA:HPACnucleoplasm
GO:0005634 IDA:HGNCCnucleus
GO:0005524 IEA:UniProtKB-KWFATP binding
GO:0016301 IDA:HGNCFkinase activity
GO:0046872 IEA:UniProtKB-KWFmetal ion binding
GO:0004672 IMP:UniProtKBFprotein kinase activity
GO:0004674 IBA:GO_CentralFprotein serine/threonine kinase activity
GO:0044770 IMP:BHF-UCLPcell cycle phase transition
GO:0051301 IEA:UniProtKB-KWPcell division
GO:0006260 TAS:ReactomePDNA replication
GO:0006270 IBA:GO_CentralPDNA replication initiation
GO:0000727 IBA:GO_CentralPdouble-strand break repair via break-induced replication
GO:0000082 TAS:ReactomePG1/S transition of mitotic cell cycle
GO:0000278 TAS:ReactomePmitotic cell cycle
GO:0018105 IBA:GO_CentralPpeptidyl-serine phosphorylation
GO:0006909 IBA:GO_CentralPphagocytosis
GO:0008284 IMP:HGNCPpositive regulation of cell proliferation
GO:0010971 IMP:UniProtKBPpositive regulation of G2/M transition of mitotic cell cycle
GO:0010571 IMP:UniProtKBPpositive regulation of nuclear cell cycle DNA replication
GO:0008360 IBA:GO_CentralPregulation of cell shape
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_6769Activation of ATR in response to replication stress
REACT_1095Activation of the pre-replicative complex
REACT_115566Cell Cycle
REACT_1538Cell Cycle Checkpoints
REACT_152Cell Cycle, Mitotic
REACT_383DNA Replication
REACT_734DNA Replication Pre-Initiation
REACT_1783G1/S Transition
REACT_828G2/M Checkpoints
REACT_1725M/G1 Transition
REACT_21267Mitotic G1-G1/S phases
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