MGP Database

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MGP003553

Ontology/Pathway Information

Entrez Gene ID8440
Gene NameNCK adaptor protein 2
Gene Symbol NCK2
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005737 NAS:UniProtKBCcytoplasm
GO:0005829 TAS:ReactomeCcytosol
GO:0005783 IDA:ParkinsonsUK-UCLCendoplasmic reticulum
GO:0012506 IEA:EnsemblCvesicle membrane
GO:0008093 NAS:UniProtKBFcytoskeletal adaptor activity
GO:0030159 NAS:UniProtKBFreceptor signaling complex scaffold activity
GO:0005070 NAS:ParkinsonsUK-UCLFSH3/SH2 adaptor activity
GO:0007015 IEA:EnsemblPactin filament organization
GO:0007411 TAS:ReactomePaxon guidance
GO:0016477 IEA:EnsemblPcell migration
GO:0007173 TAS:ProtIncPepidermal growth factor receptor signaling pathway
GO:0030032 IEA:EnsemblPlamellipodium assembly
GO:0008285 TAS:ProtIncPnegative regulation of cell proliferation
GO:0033137 IDA:ParkinsonsUK-UCLPnegative regulation of peptidyl-serine phosphorylation
GO:0030838 IMP:UniProtKBPpositive regulation of actin filament polymerization
GO:0009967 NAS:GOCPpositive regulation of signal transduction
GO:0042102 IMP:UniProtKBPpositive regulation of T cell proliferation
GO:0045944 IDA:UniProtKBPpositive regulation of transcription from RNA polymerase II promoter
GO:0060734 IDA:ParkinsonsUK-UCLPregulation of eIF2 alpha phosphorylation by endoplasmic reticulum stress
GO:0007176 TAS:ProtIncPregulation of epidermal growth factor-activated receptor activity
GO:0006417 IEA:UniProtKB-KWPregulation of translation
GO:0007172 NAS:UniProtKBPsignal complex assembly
GO:0007165 TAS:ProtIncPsignal transduction
GO:0042110 NAS:UniProtKBPT cell activation
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_19226Activation of Rac
REACT_18266Axon guidance
REACT_111155Cell-Cell communication
REACT_111045Developmental Biology
REACT_17025Downstream signal transduction
REACT_264068EPH-Ephrin signaling
REACT_264047Ephrin signaling
REACT_23832Nephrin interactions
REACT_16888Signaling by PDGF
REACT_19351Signaling by Robo receptor
REACT_12529Signaling by VEGF
REACT_111102Signal Transduction
REACT_264464VEGFA-VEGFR2 Pathway
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