MGP Database

New search | Record Overview | Ontology/Pathway Information | Domain Information | UniProt Annotations | Related Proteins
MGP004317

Ontology/Pathway Information

Entrez Gene ID10637
Gene Nameleft-right determination factor 1
Gene Symbol LEFTY1
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005615 IBA:GO_CentralCextracellular space
GO:0005125 IBA:GO_CentralFcytokine activity
GO:0005160 IBA:GO_CentralFtransforming growth factor beta receptor binding
GO:0048468 IBA:GO_CentralPcell development
GO:0016049 IEA:InterProPcell growth
GO:0007368 ISS:BHF-UCLPdetermination of left/right symmetry
GO:0003007 ISS:BHF-UCLPheart morphogenesis
GO:0000122 ISS:BHF-UCLPnegative regulation of transcription from RNA polymerase II promoter
GO:0010862 IBA:GO_CentralPpositive regulation of pathway-restricted SMAD protein phosphorylation
GO:0042981 IBA:GO_CentralPregulation of apoptotic process
GO:0043408 IBA:GO_CentralPregulation of MAPK cascade
GO:0060395 IBA:GO_CentralPSMAD protein signal transduction
GO:0007179 TAS:ProtIncPtransforming growth factor beta receptor signaling pathway
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_111045Developmental Biology
REACT_111059Regulation of signaling by NODAL
REACT_111057Signaling by NODAL
  logo