MGP Database

New search | Record Overview | Ontology/Pathway Information | Domain Information | UniProt Annotations | Related Proteins
MGP004317

UniProt Annotations

Entry Information
Gene Nameleft-right determination factor 1
Protein EntryLFTY1_HUMAN
UniProt IDO75610
SpeciesHuman
Comments
Comment typeDescription
FunctionRequired for left-right axis determination as a regulator of LEFTY2 and NODAL.
PtmThe processing of the protein may also occur at the second R- X-X-R site located at AA 132-135. Processing appears to be regulated in a cell-type specific manner.
SimilarityBelongs to the TGF-beta family. {ECO:0000305}.
Subcellular LocationSecreted.
  logo