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MGP006046

Record overview

MGPD IDMGP006046
Gene ID81603
SpeciesHomo sapiens (Human)
Gene Nametripartite motif containing 8
Gene Symbol TRIM8
SynonymsGERP; RNF27;
Alternate namesprobable E3 ubiquitin-protein ligase TRIM8; glioblastoma expressed ring finger protein; glioblastoma-expressed RING finger protein; ring finger protein 27; tripartite motif protein TRIM8; tripartite motif-containing 8; tripartite motif-containing protein 8;
Chromosome10
Map Location10q24.3
EC Number6.3.2.-
SummaryThe protein encoded by this gene is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. This protein localizes to nuclear bodies. Its structure is similar to some tumor suppressor proteins and its gene maps to a locus thought to contain tumor suppressor genes. [provided by RefSeq, Jul 2008]
OrthologsView orthologs and multiple alignments for TRIM8

Proteins

probable E3 ubiquitin-protein ligase TRIM8
Refseq ID:NP_112174
Protein GI:148596968
UniProt ID:Q9BZR9
mRNA ID:NM_030912
Length:551
RefSeq Status:
MAENWKNCFEEELICPICLHVFVEPVQLPCKHNFCRGCIGEAWAKDSGLVRCPECNQAYNQKPGLEKNLKLTNIVEKFNALHVEKPPAALHCVFCRRGPP
LPAQKVCLRCEAPCCQSHVQTHLQQPSTARGHLLVEADDVRAWSCPQHNAYRLYHCEAEQVAVCQYCCYYSGAHQGHSVCDVEIRRNEIRKMLMKQQDRL
EEREQDIEDQLYKLESDKRLVEEKVNQLKEEVRLQYEKLHQLLDEDLRQTVEVLDKAQAKFCSENAAQALHLGERMQEAKKLLGSLQLLFDKTEDVSFMK
NTKSVKILMDRTQTCTSSSLSPTKIGHLNSKLFLNEVAKKEKQLRKMLEGPFSTPVPFLQSVPLYPCGVSSSGAEKRKHSTAFPEASFLETSSGPVGGQY
GAAGTASGEGQSGQPLGPCSSTQHLVALPGGAQPVHSSPVFPPSQYPNGSAAQQPMLPQYGGRKILVCSVDNCYCSSVANHGGHQPYPRSGHFPWTVPSQ
EYSHPLPPTPSVPQSLPSLAVRDWLDASQQPGHQDFYRVYGQPSTKHYVTS
 
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