MGP Database

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MGP006046

Ontology/Pathway Information

Entrez Gene ID81603
Gene Nametripartite motif containing 8
Gene Symbol TRIM8
SpeciesHomo sapiens
Gene Ontology (GO Annotations)
GO IDSourceTypeDescription
GO:0005737 IDA:HPACcytoplasm
GO:0043231 IDA:HPACintracellular membrane-bounded organelle
GO:0005654 IDA:HPACnucleoplasm
GO:0016605 IDA:UniProtKBCPML body
GO:0042802 IPI:IntActFidentical protein binding
GO:0016874 IEA:UniProtKB-KWFligase activity
GO:0042803 IPI:UniProtKBFprotein homodimerization activity
GO:0008270 NAS:UniProtKBFzinc ion binding
GO:0045087 IDA:UniProtKBPinnate immune response
GO:0046597 IEA:EnsemblPnegative regulation of viral entry into host cell
GO:1902187 IDA:UniProtKBPnegative regulation of viral release from host cell
GO:0032897 IEA:EnsemblPnegative regulation of viral transcription
GO:0043123 IDA:UniProtKBPpositive regulation of I-kappaB kinase/NF-kappaB signaling
GO:0051092 IDA:UniProtKBPpositive regulation of NF-kappaB transcription factor activity
GO:0051091 IDA:UniProtKBPpositive regulation of sequence-specific DNA binding transcription factor activity
GO:0016567 IEA:UniProtKB-UniPathwayPprotein ubiquitination
REACTOME Pathway Links
REACTOME Pathway IDDescription
REACT_75790Cytokine Signaling in Immune system
REACT_6900Immune System
REACT_25078Interferon gamma signaling
REACT_25229Interferon Signaling
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