Summary of Study ST001323
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000900. The data can be accessed directly via it's Project DOI: 10.21228/M8BX09 This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
Study ID | ST001323 |
Study Title | Effect of high-fat diet on serum lipidome in mice |
Study Summary | We analyzed mouse serum samples from a mouse dietary intervention experiment. Briefly, C57BL/6 mice (n=44) were divided into 4 groups (n=11 per group) and fed High-fat diet (HFD), 1% deoxycholic acid (DCA) in drinking water, both, or left as control for 9 months. For quality control, 12 TQC samples and 2 blanks were also included in the analysis (total 58 samples and 6 groups). The two treatments were selected to demonstrate the ability of lipidomics to detect gross changes induced by HFD in the serum lipidome, as well as specific/minor changes induced by the secondary bile acid (DCA) through regulation of liver lipid metabolism. |
Institute | QIMR Berghofer Medical Research Institute |
Last Name | Mohamed |
First Name | Ahmed |
Address | 300 Herston Road |
ahmed.mohamed@qimrberghofer.edu.au | |
Phone | +61738453992 |
Submit Date | 2020-03-02 |
Raw Data Available | Yes |
Raw Data File Type(s) | d |
Analysis Type Detail | LC-MS |
Release Date | 2020-03-20 |
Release Version | 1 |
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Project:
Project ID: | PR000900 |
Project DOI: | doi: 10.21228/M8BX09 |
Project Title: | Effect of high-fat diet on serum lipidome in mice |
Project Summary: | We analyzed mouse serum samples from a mouse dietary intervention experiment. Briefly, C57BL/6 mice (n=44) were divided into 4 groups (n=11 per group) and fed High-fat diet (HFD), 1% deoxycholic acid (DCA) in drinking water, both, or left as control for 9 months. For quality control, 12 TQC samples and 2 blanks were also included in the analysis (total 58 samples and 6 groups). The two treatments were selected to demonstrate the ability of lipidomics to detect gross changes induced by HFD in the serum lipidome, as well as specific/minor changes induced by the secondary bile acid (DCA) through regulation of liver lipid metabolism. |
Institute: | QIMR Berghofer Medical Research Institute |
Department: | Precision & Systems Biomedicine |
Last Name: | Mohamed |
First Name: | Ahmed |
Address: | 300 Herston Road, Herston, QLD, 4006, Australia |
Email: | ahmed.mohamed@qimrberghofer.edu.au |
Phone: | +61738453992 |