Summary of Study ST001413

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000969. The data can be accessed directly via it's Project DOI: 10.21228/M8FD5Z This work is supported by NIH grant, U2C- DK119886.

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Study IDST001413
Study TitleMetabolomic and Transcriptomic Signatures of Prenatal Excessive Methionine in Mice
Study TypeMS Analysis
Study SummaryMicronutrients are key regulators of prenatal one-carbon (C1) metabolism. We show here that prenatal excessive methionine (MET), a principal micronutrient and methyl-donor, produces in early life stages significant changes in the components of brain C1 pathways and other metabolic pathways including glutamate transmission, mitochondrial function, and lipid metabolism.
Institute
University of California, Irvine
DepartmentDepartment of Pharmaceutical Sciences and Department of Computer Science
LaboratoryAmal Alachkar Group. Pierre Baldi Group
Last NameChen
First NameSiwei
Address66304 Verano Place Rd. South
Emailsiweic@uci.edu
Phone2066585923
Submit Date2020-06-24
Num Groups4
Total Subjects28
Num Males28
Raw Data AvailableYes
Raw Data File Type(s)wiff
Analysis Type DetailLC-MS
Release Date2020-07-24
Release Version1
Siwei Chen Siwei Chen
https://dx.doi.org/10.21228/M8FD5Z
ftp://www.metabolomicsworkbench.org/Studies/ application/zip

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Combined analysis:

Analysis ID AN002363
Analysis type MS
Chromatography type HILIC
Chromatography system SCIEX 6600TTOF
Column Thermo Accucore HILIC (100 x 2.1mm,2.6um)
MS Type APCI
MS instrument type Triple TOF
MS instrument name ABI Sciex 6600 TripleTOF
Ion Mode POSITIVE
Units m/z

Chromatography:

Chromatography ID:CH001733
Instrument Name:SCIEX 6600TTOF
Column Name:Thermo Accucore HILIC (100 x 2.1mm,2.6um)
Chromatography Type:HILIC
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