Summary of Study ST001413

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench,, where it has been assigned Project ID PR000969. The data can be accessed directly via it's Project DOI: 10.21228/M8FD5Z This work is supported by NIH grant, U2C- DK119886.


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Study IDST001413
Study TitleMetabolomic and Transcriptomic Signatures of Prenatal Excessive Methionine in Mice
Study TypeMS Analysis
Study SummaryMicronutrients are key regulators of prenatal one-carbon (C1) metabolism. We show here that prenatal excessive methionine (MET), a principal micronutrient and methyl-donor, produces in early life stages significant changes in the components of brain C1 pathways and other metabolic pathways including glutamate transmission, mitochondrial function, and lipid metabolism.
University of California, Irvine
DepartmentDepartment of Pharmaceutical Sciences and Department of Computer Science
LaboratoryAmal Alachkar Group. Pierre Baldi Group
Last NameChen
First NameSiwei
Address66304 Verano Place Rd. South
Submit Date2020-06-24
Num Groups4
Total Subjects28
Num Males28
Raw Data AvailableYes
Raw Data File Type(s)wiff
Analysis Type DetailLC-MS
Release Date2020-07-24
Release Version1
Siwei Chen Siwei Chen application/zip

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Subject type: Mammal; Subject species: Mus musculus (Factor headings shown in green)

mb_sample_id local_sample_id Condition Age
SA115960Adult2Control 13 weeks
SA115961Adult1Control 13 weeks
SA115962Adult6Control 13 weeks
SA115963Adult5Control 13 weeks
SA115964Adult3Control 13 weeks
SA115965Adult4Control 13 weeks
SA115966Newborn4Control 24 hour
SA115967Newborn5Control 24 hour
SA115968Newborn2Control 24 hour
SA115969Newborn8Control 24 hour
SA115970Newborn7Control 24 hour
SA115971Newborn6Control 24 hour
SA115972Newborn3Control 24 hour
SA115973Newborn1Control 24 hour
SA115974Adult7Methionine 13 weeks
SA115975Adult8Methionine 13 weeks
SA115976Adult9Methionine 13 weeks
SA115977Adult12Methionine 13 weeks
SA115978Adult11Methionine 13 weeks
SA115979Adult10Methionine 13 weeks
SA115980Newborn15Methionine 24 hour
SA115981Newborn16Methionine 24 hour
SA115982Newborn14Methionine 24 hour
SA115983Newborn10Methionine 24 hour
SA115984Newborn9Methionine 24 hour
SA115985Newborn11Methionine 24 hour
SA115986Newborn12Methionine 24 hour
SA115987Newborn13Methionine 24 hour
Showing results 1 to 28 of 28