Summary of Study ST001413

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench,, where it has been assigned Project ID PR000969. The data can be accessed directly via it's Project DOI: 10.21228/M8FD5Z This work is supported by NIH grant, U2C- DK119886.


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Study IDST001413
Study TitleMetabolomic and Transcriptomic Signatures of Prenatal Excessive Methionine in Mice
Study TypeMS Analysis
Study SummaryMicronutrients are key regulators of prenatal one-carbon (C1) metabolism. We show here that prenatal excessive methionine (MET), a principal micronutrient and methyl-donor, produces in early life stages significant changes in the components of brain C1 pathways and other metabolic pathways including glutamate transmission, mitochondrial function, and lipid metabolism.
University of California, Irvine
DepartmentDepartment of Pharmaceutical Sciences and Department of Computer Science
LaboratoryAmal Alachkar Group. Pierre Baldi Group
Last NameChen
First NameSiwei
Address66304 Verano Place Rd. South
Submit Date2020-06-24
Num Groups4
Total Subjects28
Num Males28
Raw Data AvailableYes
Raw Data File Type(s)wiff
Analysis Type DetailLC-MS
Release Date2020-07-24
Release Version1
Siwei Chen Siwei Chen application/zip

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Subject ID:SU001487
Subject Type:Mammal
Subject Species:Mus musculus
Taxonomy ID:10090
Age Or Age Range:newborn mice of 24hr old or adult mice of 13 week old
Animal Animal Supplier:Charles River Laboratories (Wilmington, MA)