Summary of Study ST001436
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000987. The data can be accessed directly via it's Project DOI: 10.21228/M8410G This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.
| Study ID | ST001436 |
| Study Title | Transkingdom interactions between Lactobacilli and hepatic mitochondria attenuate western diet induced diabetes |
| Study Type | Supplementation of mice with probiotic bacteria |
| Study Summary | For WD + Microbes 1 and WD + Microbes 3 experiments, C57BL/6 mice were fed western diet or western diet supplemented with Lactobacillus gasseri or Lactobacillus johnsonii for 8 weeks and serum was collected from each mice. For Pooled_1 (control group, western diet only), and Pooled_2 (western diet + Lactobacillus gasseri) groups, serum from 5 mice each was pooled. For Pooled_3 (western diet + Lactobacillus johnsonii) group, serum from 4 mice was pooled. For Pooled_7 (control group, western diet only), Pooled_8 (western diet + Lactobacillus gasseri) and Pooled_9 (western diet + Lactobacillus johnsonii) groups, serum from 6 mice each was pooled. For WD + Microbes 6 experiment, C57BL/6 mice were fed western diet for 8 weeks. Then, one group (n = 5) of mice was supplemented with Lactobacillus gasseri for 12 weeks along with continuation of western diet and serum was collected. For Pooled_10 (control group, western diet only) and Pooled_11 (western diet + Lactobacillus gasseri) groups, serum from 5 mice each was pooled. For GF + WD + LG experiment, C57BL/6 germ free mice were fed western diet or western diet supplemented with Lactobacillus gasseri for 2 weeks. For Pooled_12 (control, western diet only) and Pooled_13 (western diet + Lactobacillus gasseri) groups, serum from 2 mice each was pooled. |
| Institute | Oregon State University |
| Department | Pharmaceutical Sciences |
| Laboratory | Morgun and Shulzhenko |
| Last Name | Morgun |
| First Name | Andriy |
| Address | 203 Pharmacy Bldg |
| andriy.morgun@oregonstate.edu | |
| Phone | 1 541 737 8047 |
| Submit Date | 2020-07-28 |
| Num Groups | 7 |
| Raw Data Available | Yes |
| Raw Data File Type(s) | d |
| Analysis Type Detail | LC-MS |
| Release Date | 2020-09-21 |
| Release Version | 1 |
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Collection:
| Collection ID: | CO001505 |
| Collection Summary: | After the end of the experiment, whole blood was collected in BD Microtainer Serum Separator Tube and allowed to clot by leaving undistubred at room temperature for 30 minutes. Then the tubes were centrifuged at 2000 x g for 10 minutes in 4°C and the supernatant was immediately transferred into a polypropylene tube and stored at -80°C until further analysis. |
| Sample Type: | Blood (serum) |
| Storage Conditions: | -80℃ |
