Summary of Study ST001436

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000987. The data can be accessed directly via it's Project DOI: 10.21228/M8410G This work is supported by NIH grant, U2C- DK119886.

See: https://www.metabolomicsworkbench.org/about/howtocite.php

This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.

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Study IDST001436
Study TitleTranskingdom interactions between Lactobacilli and hepatic mitochondria attenuate western diet induced diabetes
Study TypeSupplementation of mice with probiotic bacteria
Study SummaryFor WD + Microbes 1 and WD + Microbes 3 experiments, C57BL/6 mice were fed western diet or western diet supplemented with Lactobacillus gasseri or Lactobacillus johnsonii for 8 weeks and serum was collected from each mice. For Pooled_1 (control group, western diet only), and Pooled_2 (western diet + Lactobacillus gasseri) groups, serum from 5 mice each was pooled. For Pooled_3 (western diet + Lactobacillus johnsonii) group, serum from 4 mice was pooled. For Pooled_7 (control group, western diet only), Pooled_8 (western diet + Lactobacillus gasseri) and Pooled_9 (western diet + Lactobacillus johnsonii) groups, serum from 6 mice each was pooled. For WD + Microbes 6 experiment, C57BL/6 mice were fed western diet for 8 weeks. Then, one group (n = 5) of mice was supplemented with Lactobacillus gasseri for 12 weeks along with continuation of western diet and serum was collected. For Pooled_10 (control group, western diet only) and Pooled_11 (western diet + Lactobacillus gasseri) groups, serum from 5 mice each was pooled. For GF + WD + LG experiment, C57BL/6 germ free mice were fed western diet or western diet supplemented with Lactobacillus gasseri for 2 weeks. For Pooled_12 (control, western diet only) and Pooled_13 (western diet + Lactobacillus gasseri) groups, serum from 2 mice each was pooled.
Institute
Oregon State University
DepartmentPharmaceutical Sciences
LaboratoryMorgun and Shulzhenko
Last NameMorgun
First NameAndriy
Address203 Pharmacy Bldg
Emailandriy.morgun@oregonstate.edu
Phone1 541 737 8047
Submit Date2020-07-28
Num Groups7
Raw Data AvailableYes
Raw Data File Type(s)d
Analysis Type DetailLC-MS
Release Date2020-09-21
Release Version1
Andriy Morgun Andriy Morgun
https://dx.doi.org/10.21228/M8410G
ftp://www.metabolomicsworkbench.org/Studies/ application/zip

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Factors:

Subject type: Mammal; Subject species: Mus musculus (Factor headings shown in green)

mb_sample_id local_sample_id Treatment
SA122008Sample_01Western diet
SA122009Sample_12Western diet
SA122010Sample_07Western diet
SA122011Sample_10Western diet
SA122012Sample_11Western diet + Lactobacillus gasseri
SA122013Sample_08Western diet + Lactobacillus gasseri
SA122014Sample_02Western diet + Lactobacillus gasseri
SA122015Sample_13Western diet + Lactobacillus gasseri
SA122016Sample_09Western diet + Lactobacillus johnsonii
SA122017Sample_03Western diet + Lactobacillus johnsonii
Showing results 1 to 10 of 10
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