Summary of Study ST001948

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench,, where it has been assigned Project ID PR001235. The data can be accessed directly via it's Project DOI: 10.21228/M82T49 This work is supported by NIH grant, U2C- DK119886.


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Study IDST001948
Study TitleMetabolites Associated with Gestational Diabetes in Plasma
Study TypeCase:Control ancillary analysis of RCT
Study SummaryGestational diabetes mellitus (GDM) significantly increases maternal and fetal health risks, but factors predictive of GDM are poorly understood. Plasma metabolomics analyses were conducted in early pregnancy to identify potential biomarkers for early prediction of Gestational Diabetes Mellitus (GDM). Sixty-eight pregnant women with overweight/obesity from a clinical trial of a lifestyle intervention were included. Participants who developed GDM (n=34; GDM group) were matched on treatment group, age, body mass index, and ethnicity with those who did not develop GDM (n=34; Non-GDM group). Blood draws were completed early in pregnancy (10-16 weeks). Plasma samples were analyzed by UPLC-MS using three metabolomics assays.
California Polytechnic State University
DepartmentFood Science and Nutrition
LaboratoryCal Poly Metabolomics Service Center
Last NameLa Frano
First NameMichael
Submit Date2021-10-13
Num Groups2
Total Subjects68
Num Females68
Raw Data AvailableYes
Raw Data File Type(s)mzML
Analysis Type DetailLC-MS
Release Date2021-11-04
Release Version1
Michael La Frano Michael La Frano application/zip

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Subject type: Human; Subject species: Homo sapiens (Factor headings shown in green)

mb_sample_id local_sample_id Species Case-Control Time Treatment (1=control, 2=treatment)
SA183796B39Human GDM 1st Trimester 1
SA183797B66Human GDM 1st Trimester 1
SA183798C39Human GDM 1st Trimester 1
SA183799B24Human GDM 1st Trimester 1
SA183800B8Human GDM 1st Trimester 1
SA183801B4Human GDM 1st Trimester 1
SA183802B33Human GDM 1st Trimester 1
SA183803C4Human GDM 1st Trimester 1
SA183804C12Human GDM 1st Trimester 1
SA183805C28Human GDM 1st Trimester 1
SA183806C17Human GDM 1st Trimester 1
SA183807B42Human GDM 1st Trimester 1
SA183808B57Human GDM 1st Trimester 1
SA183809C31Human GDM 1st Trimester 1
SA183810B54Human GDM 1st Trimester 1
SA183811C30Human GDM 1st Trimester 1
SA183812B12-REPAVGHuman GDM 1st Trimester 1
SA183813B23Human GDM 1st Trimester 2
SA183814B44Human GDM 1st Trimester 2
SA183815B62Human GDM 1st Trimester 2
SA183816B47Human GDM 1st Trimester 2
SA183817B40-REPAVGHuman GDM 1st Trimester 2
SA183818B18Human GDM 1st Trimester 2
SA183819B49Human GDM 1st Trimester 2
SA183820B7Human GDM 1st Trimester 2
SA183821C41Human GDM 1st Trimester 2
SA183822B25-REPAVGHuman GDM 1st Trimester 2
SA183823C32Human GDM 1st Trimester 2
SA183824B56Human GDM 1st Trimester 2
SA183825C24Human GDM 1st Trimester 2
SA183826C35Human GDM 1st Trimester 2
SA183827C2Human GDM 1st Trimester 2
SA183828C14Human GDM 1st Trimester 2
SA183829B53Human GDM 1st Trimester 2
SA183830C13Human No_GDM 1st Trimester 1
SA183831C20Human No_GDM 1st Trimester 1
SA183832C21Human No_GDM 1st Trimester 1
SA183833B65Human No_GDM 1st Trimester 1
SA183834C29Human No_GDM 1st Trimester 1
SA183835B29Human No_GDM 1st Trimester 1
SA183836C11Human No_GDM 1st Trimester 1
SA183837B60Human No_GDM 1st Trimester 1
SA183838B74Human No_GDM 1st Trimester 1
SA183839B70Human No_GDM 1st Trimester 1
SA183840B50Human No_GDM 1st Trimester 1
SA183841C40Human No_GDM 1st Trimester 1
SA183842B2Human No_GDM 1st Trimester 1
SA183843C18Human No_GDM 1st Trimester 1
SA183844B26Human No_GDM 1st Trimester 1
SA183845B21Human No_GDM 1st Trimester 1
SA183846B13Human No_GDM 1st Trimester 1
SA183847C23-REP AVGHuman No_GDM 1st Trimester 2
SA183848C43Human No_GDM 1st Trimester 2
SA183849B16Human No_GDM 1st Trimester 2
SA183850B5Human No_GDM 1st Trimester 2
SA183851B45Human No_GDM 1st Trimester 2
SA183852B69Human No_GDM 1st Trimester 2
SA183853B73Human No_GDM 1st Trimester 2
SA183854B51Human No_GDM 1st Trimester 2
SA183855B36Human No_GDM 1st Trimester 2
SA183856B67Human No_GDM 1st Trimester 2
SA183857B41Human No_GDM 1st Trimester 2
SA183858C10Human No_GDM 1st Trimester 2
SA183859C19Human No_GDM 1st Trimester 2
SA183860C1-REPAVGHuman No_GDM 1st Trimester 2
SA183861B34Human No_GDM 1st Trimester 2
SA183862B55Human No_GDM 1st Trimester 2
SA183863C5Human No_GDM 1st Trimester 2
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