Summary of Study ST002772
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001729. The data can be accessed directly via it's Project DOI: 10.21228/M86X4K This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.
| Study ID | ST002772 |
| Study Title | Day-night fluctuations in Cerebrospinal fluid metabolomics |
| Study Type | Circadian (Naïve animals) |
| Study Summary | This study was designed to investigate whether the molecular drivers underlying the diurnal fluctuation of CSF secretion rate could be found in either the choroid plexus tissue itself and/or in the CSF surrounding it. Male Sprague-Dawley rats, kept in light-controlled 12:12 conditions, presented with diurnally modulated CSF metabolite composition. This change was accompanied with differential expression of 2778 genes within the choroid plexus, with several plasma membrane transporters and CLOCK-associated genes diurnally modulated. |
| Institute | University of Copenhagen |
| Department | Department of Neuroscience |
| Laboratory | MacAulay Group |
| Last Name | Edelbo |
| First Name | Beatriche |
| Address | Blegdamsvej 3B |
| beatriche.henriksen@sund.ku.dk | |
| Phone | +4527697585 |
| Submit Date | 2023-07-04 |
| Num Groups | 2 |
| Total Subjects | 25 |
| Num Males | 25 |
| Study Comments | 2 night animals were excluded due to comments regarding sampling/behavior (N4 and N11) |
| Publications | Day-night fluctuations in choroid plexus transcriptomics and cerebrospinal fluid metabolomics |
| Raw Data Available | Yes |
| Raw Data File Type(s) | mzML, raw(Thermo) |
| Analysis Type Detail | LC-MS |
| Release Date | 2023-07-25 |
| Release Version | 1 |
Select appropriate tab below to view additional metadata details:
Factors:
Subject type: Mammal; Subject species: Rattus norvegicus (Factor headings shown in green)
| mb_sample_id | local_sample_id | factor |
|---|---|---|
| SA294432 | N2 | Dark phase sample |
| SA294433 | N4 | Dark phase sample |
| SA294434 | N3 | Dark phase sample |
| SA294435 | N10 | Dark phase sample |
| SA294436 | ?N1 | Dark phase sample |
| SA294437 | N1 | Dark phase sample |
| SA294438 | N5 | Dark phase sample |
| SA294439 | N6 | Dark phase sample |
| SA294440 | ?N3 | Dark phase sample |
| SA294441 | ?N2 | Dark phase sample |
| SA294442 | N9 | Dark phase sample |
| SA294443 | ?N4 | Dark phase sample |
| SA294444 | N7 | Dark phase sample |
| SA294445 | N8 | Dark phase sample |
| SA294446 | D8 | Light phase sample |
| SA294447 | D9 | Light phase sample |
| SA294448 | D7 | Light phase sample |
| SA294449 | D4 | Light phase sample |
| SA294450 | D10 | Light phase sample |
| SA294451 | D6 | Light phase sample |
| SA294452 | D11 | Light phase sample |
| SA294453 | D1 | Light phase sample |
| SA294454 | D2 | Light phase sample |
| SA294455 | D5 | Light phase sample |
| SA294456 | D3 | Light phase sample |
| SA294457 | QC2 | Pooled samples - quality control |
| SA294458 | QC1 | Pooled samples - quality control |
| SA294459 | QC3 | Pooled samples - quality control |
| SA294460 | QC6 | Pooled samples - quality control |
| SA294461 | QC | Pooled samples - quality control |
| SA294462 | QC5 | Pooled samples - quality control |
| SA294463 | QC4 | Pooled samples - quality control |
| Showing results 1 to 32 of 32 |
