Summary of Study ST002772
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001729. The data can be accessed directly via it's Project DOI: 10.21228/M86X4K This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.
| Study ID | ST002772 |
| Study Title | Day-night fluctuations in Cerebrospinal fluid metabolomics |
| Study Type | Circadian (Naïve animals) |
| Study Summary | This study was designed to investigate whether the molecular drivers underlying the diurnal fluctuation of CSF secretion rate could be found in either the choroid plexus tissue itself and/or in the CSF surrounding it. Male Sprague-Dawley rats, kept in light-controlled 12:12 conditions, presented with diurnally modulated CSF metabolite composition. This change was accompanied with differential expression of 2778 genes within the choroid plexus, with several plasma membrane transporters and CLOCK-associated genes diurnally modulated. |
| Institute | University of Copenhagen |
| Department | Department of Neuroscience |
| Laboratory | MacAulay Group |
| Last Name | Edelbo |
| First Name | Beatriche |
| Address | Blegdamsvej 3B |
| beatriche.henriksen@sund.ku.dk | |
| Phone | +4527697585 |
| Submit Date | 2023-07-04 |
| Num Groups | 2 |
| Total Subjects | 25 |
| Num Males | 25 |
| Study Comments | 2 night animals were excluded due to comments regarding sampling/behavior (N4 and N11) |
| Publications | Day-night fluctuations in choroid plexus transcriptomics and cerebrospinal fluid metabolomics |
| Raw Data Available | Yes |
| Raw Data File Type(s) | mzML, raw(Thermo) |
| Analysis Type Detail | LC-MS |
| Release Date | 2023-07-25 |
| Release Version | 1 |
Select appropriate tab below to view additional metadata details:
Sample Preparation:
| Sampleprep ID: | SP002885 |
| Sampleprep Summary: | No sample prep was done after freezing. |
