Summary of Study ST001214
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000811. The data can be accessed directly via it's Project DOI: 10.21228/M8VD62 This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
| Study ID | ST001214 |
| Study Title | Lipidommics in the serum of human subjects |
| Study Summary | We aimed to determine the levels of the cold-induced 12-LOX products in patients with different degrees of body mass index (BMI). This analysis allowed us to infer about the role of these oxylipins in the pathophysiology of obesity. |
| Institute | Joslin Diabetes Center |
| Last Name | Leiria |
| First Name | Luiz |
| Address | One Joslin Place, 02215, Boston-MA - USA |
| luiz.leiria@joslin.harvard.edu | |
| Phone | 617-309-1967 |
| Submit Date | 2019-07-10 |
| Raw Data Available | Yes |
| Raw Data File Type(s) | wiff |
| Analysis Type Detail | LC-MS |
| Release Date | 2019-09-23 |
| Release Version | 1 |
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Project:
| Project ID: | PR000811 |
| Project DOI: | doi: 10.21228/M8VD62 |
| Project Title: | 12-LOX metabolites in cold adaptation |
| Project Summary: | The goal of this project is to understand the role of the enzyme 12-lipoxygenase in the adaptive thermogenesis. We found this enzyme is activated by cold stimulation, then producing lipid metabolites in adipose tissue and releasing them into the circulation to regulate fuel utilisation and thermogenic pathways required for the cold adaptation. |
| Institute: | Joslin Diabetes Center |
| Department: | Integrative Physiology and Metabolism |
| Laboratory: | Yu-Hua Tseng lab |
| Last Name: | Leiria |
| First Name: | Luiz |
| Address: | One Joslin Place, Boston, MA-USA, 02215 |
| Email: | luiz.leiri@joslin.harvard.edu |
| Phone: | 1 6173091967 |
