Summary of Study ST000093
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000085. The data can be accessed directly via it's Project DOI: 10.21228/M8JS3X This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
| Study ID | ST000093 |
| Study Title | Metabolomics Analysis of Frontal Fibrosing Alopecia |
| Study Type | Unaffected and Affected patient scalp biopsies |
| Study Summary | Scarring alopecia consists of a collection of disorders characterized by destruction of hair follicles, replacement with fibrous scar tissue, and irreversible hair loss. Alopecia affects men and women worldwide and can be a significant source of psychological stress and depression for affected individuals. The purpose of this study was to explore metabolic profiles in scalp tissue samples from normal control subjects (n=6) and in matched samples obtained from affected (n=12) and unaffected (n=12) areas of the scalp in patients with lymphocytic Frontal Fibrosing Alopecia (FFA). Frontal fibrosing alopecia results from destruction of hair follicles by an inflammatory lymphocytic infiltrate that is localized around the upper portion of the hair follicle. |
| Institute | Case Western Reserve University |
| Department | Dermatology |
| Laboratory | Karnik Lab |
| Last Name | Karnik |
| First Name | Pratima |
| psk11@case.edu | |
| Phone | 216-368-0209 |
| Submit Date | 2014-07-24 |
| Num Groups | 3 groups-Paired unaffected and affected (n=12),Normals(n=6) |
| Total Subjects | Patients (N=12), Normals (N=6) |
| Study Comments | Affected scalp biopsies were obtained from frontal scalp, Unaffected from occipital scalp. Normal scalp biopsies were obtained from the occipital scalp. |
| Raw Data Available | No |
| Analysis Type Detail | GC-MS/LC-MS |
| Release Date | 2014-07-26 |
| Release Version | 1 |
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Collection:
| Collection ID: | CO000095 |
| Collection Summary: | - |
| Sample Type: | 4 mm Scalp biopsies |
