Summary of Study ST002567
This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR001654. The data can be accessed directly via it's Project DOI: 10.21228/M8WX3D This work is supported by NIH grant, U2C- DK119886.
See: https://www.metabolomicsworkbench.org/about/howtocite.php
This study contains a large results data set and is not available in the mwTab file. It is only available for download via FTP as data file(s) here.
| Study ID | ST002567 |
| Study Title | Metabolomics of Human islets treated with DHT and high-glucose challenge |
| Study Summary | Dihydrotestosterone (DHT) driven Androgen receptor activation in pancreatic beta-cells leads to the amplification of GLP-1R-mediated insulin exocytosis. Here we study the impact of DHT on the metabolic architecture of human pancreatic islets upon stimulation with DHT at high (16.7mM) and low (2.8mM) Glucose. |
| Institute | Tulane University School of Medicine |
| Last Name | Qadir |
| First Name | Mirza Muhammad Fahd |
| Address | SOM RM2301/Endocrinology |
| mqadir@tulane.edu | |
| Phone | 5049884646 |
| Submit Date | 2023-04-17 |
| Raw Data Available | Yes |
| Raw Data File Type(s) | mzML |
| Analysis Type Detail | LC-MS |
| Release Date | 2023-04-19 |
| Release Version | 1 |
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Collection:
| Collection ID: | CO002661 |
| Collection Summary: | Following the incubation period, tubes were briefly centrifuged at low speed and media was withdrawn. 150mM ammonium acetate in water were added to rinse residual media (150mM ammonium acetate is an osmolarity-matching, mass spectrometry compatible rinse buffer with near-neutral pH). Tubes were centrifuged, supernatant was withdrawn, and they were frozen by immersion in liquid nitrogen and stored at -80C prior to extraction. |
| Sample Type: | Pancreas |
| Volumeoramount Collected: | 500-1000uL |
| Storage Conditions: | -80℃ |
| Storage Vials: | 1ml Eppendorf Tubes |
| Collection Tube Temp: | -40C |
| Additives: | Ammonium acetate 150mM |
