Summary of Study ST000903

This data is available at the NIH Common Fund's National Metabolomics Data Repository (NMDR) website, the Metabolomics Workbench, https://www.metabolomicsworkbench.org, where it has been assigned Project ID PR000627. The data can be accessed directly via it's Project DOI: 10.21228/M8MT2H This work is supported by NIH grant, U2C- DK119886.

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Study IDST000903
Study TitlePharmacometabolomic analysis of rat hippocampus and plasma in response to chronic stress and albiflorin treament
Study TypeAnimal study
Study SummaryMale Sprague-Dawley (SD) rats were exposed to one random stressor per day for 35 d. Following four weeks of stress exposure, rats with stress-induced depression-like behaviors were treated daily with either saline, fluoxetine or albiflorin for 7 days via intragastric gavage. Rat heparinized plasma was collected after drug treatment. After behavior tests, rats were sacrificed and the hippocampus was collected. Pharmacometabolomic analysis was conducted for both plasma and hippocampal samples
Institute
Beijing Wonner Biotech. Ltd. Co.
Last NameZhang
First NameZuoguang
AddressNo.9, Kexing Road, Fengtai, Beijing, Beijing, 101111, China
Emailleekefeng@hotmail.com
Phone86-10-65670787
Submit Date2017-11-16
Num Groups4
Study CommentsAnimal study
Analysis Type DetailLC-MS
Release Date2018-02-07
Release Version1
Zuoguang Zhang Zuoguang Zhang
https://dx.doi.org/10.21228/M8MT2H
ftp://www.metabolomicsworkbench.org/Studies/ application/zip

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Factors:

Subject type: Animal; Subject species: Rattus norvegicus (Factor headings shown in green)

mb_sample_id local_sample_id Genotype Treatment
SA052924Beta_10_4CUMS model Albiflorin
SA052925Beta_10_3CUMS model Albiflorin
SA052926Beta_10_1CUMS model Albiflorin
SA052927Beta_10_5CUMS model Albiflorin
SA052928Beta_10_2CUMS model Albiflorin
SA052929Beta_10_6CUMS model Albiflorin
SA052930Beta_10_8CUMS model Albiflorin
SA052931Beta_10_7CUMS model Albiflorin
SA052932Beta_9_4CUMS model Fluoxetine
SA052933Beta_9_3CUMS model Fluoxetine
SA052934Beta_9_5CUMS model Fluoxetine
SA052935Beta_9_2CUMS model Fluoxetine
SA052936Beta_9_7CUMS model Fluoxetine
SA052937Beta_9_1CUMS model Fluoxetine
SA052938Beta_9_8CUMS model Fluoxetine
SA052939Beta_9_6CUMS model Fluoxetine
SA052940Beta_8_9CUMS model Saline
SA052941Beta_8_4CUMS model Saline
SA052942Beta_8_3CUMS model Saline
SA052943Beta_8_1CUMS model Saline
SA052944Beta_8_5CUMS model Saline
SA052945Beta_8_2CUMS model Saline
SA052946Beta_8_6CUMS model Saline
SA052947Beta_8_8CUMS model Saline
SA052948Beta_8_7CUMS model Saline
SA052949Beta_7_15Wild-type Saline
SA052950Beta_7_13Wild-type Saline
SA052951Beta_7_3Wild-type Saline
SA052952Beta_7_12Wild-type Saline
SA052953Beta_7_7Wild-type Saline
SA052954Beta_7_11Wild-type Saline
SA052955Beta_7_8Wild-type Saline
SA052956Beta_7_4Wild-type Saline
Showing results 1 to 33 of 33
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